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Abstract QS06: Comparison Between Oximetry and Polysomnography in Identifying Airway Obstruction in Infants with Robin Sequence

2018· article· en· W2799400143 on OpenAlexaffabout
Rafael Galli

Bibliographic record

VenuePlastic & Reconstructive Surgery Global Open · 2018
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicCongenital heart defects research
Canadian institutionsMcGill University
Fundersnot available
KeywordsPolysomnographyMedicineObstructive sleep apneaApneaPulse oximetryAirway obstructionGold standard (test)AnesthesiaPediatricsAirwayInternal medicine

Abstract

fetched live from OpenAlex

PURPOSE: Polysomnography is the gold standard for the diagnosis of obstructive apnea in infants with Robin Sequence. However, its routine use is limited by cost and availability. The purpose of our study was to determine whether night-time pulse oximetry (oximetry), an inexpensive and widely available technology, could be used as a surrogate for polysomnography in identifying obstructive apnea in infants with Robin Sequence. METHODS: We reviewed all polysomnographies done in infants with Robin Sequence treated at the Montreal Children’s Hospital. We extracted the following standard data: Central Apnea Index and Mixed Obstructive Apnea Hypopnea Index (MOAHI) from polysomnography data and Desaturation Index (drops≥4%/hour, DI4%) from the oximetry done at the time of polysomnography. Symptoms of obstructive apnea were assessed with a standard questionnaire. A MOAHI≤5 was used to separate infants with no/mild obstruction from those with moderate/severe obstruction (MOAHI>5). RESULTS: We reviewed 39 polysomnographies (26 infants, age: 12.2 ± 4.8 months). Central apnea with a mild decrease in oxygenation was a frequent occurrence. All infants with a DI4%<7 events/hour (22 studies) and no significant snoring had no or mild obstructive apnea on polysomnography. In patients with DI4%>7 events/hour, 53% had moderate or severe obstruction. In the remaining infants, central events with desaturation predominated. CONCLUSION: In Robin Sequence, oximetry can identify those infants with no or mild obstructive apnea thereby decreasing the demand for polysomnography. With a DI4%>7 events/hour, polysomnography is required to differentiate between obstructive and central events. R. Galli: None.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.010
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.017

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.010
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.042
GPT teacher head0.337
Teacher spread0.295 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2018
Admission routes2
Has abstractyes

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