Fabricationof a Cell Culture Plate With a Three-Dimensional Printed Mold and Thermal Analysis of PDMS-BasedCasting Process
Why this work is in the frame
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Bibliographic record
Abstract
Abstract Polydimethylsiloxane (PDMS)-based casting method was used to fabricate PDMS cell culture platforms with molds printed by a fused deposition modeling (FDM) printer. Cell viability study indicated that the produced plates have the suitable biocompatibility, surface properties, and transparency for cell culture purposes. The molds printed from acrylonitrile-butadiene-syrene (ABS) were reusable after curing at 65 °C, but were damaged at 75 °C. To understand thermal damage to the mold at elevated temperatures, the temperature distribution in an ABS mold during the curing process was predicted using a model that considers conduction, convection, and radiation in the oven. The simulated temperature distribution was consistent with the observed mold deformation. As the maximum temperature difference in the mold did not change appreciably with the curing temperature, we consider that the thermal damage is due to the porous structure that increases the thermal expansion coefficient of the printed material. Our study demonstrated that FDM, an affordable and accessible three-dimensional (3D) printer, has great potential for rapid prototyping of custom-designed cell culture devices for biomedical research.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it