Characterization of spinal sensory circuits comprising dorsal interneuron 3 (dI3 IN) in mice.
Bibliographic record
Abstract
Dual antibody labelling is used to visualize the proteins because several 2 ° antibodies can bind to a single 1° antibody (polyclonal), forming large 1 °-2 ° antibody complexes, therefore amplifying the signal.• The palmar grasp reflex is a reflex observed in infants where the paws (in mice) and hands (in human) close when the skin is stroked.It emerges 11 weeks in utero and continues up until the age of 2-3 months in humans.It is believed to be essential in the development of voluntary hand grasp in adults.• Corticospinal tract inputs (CST; labelled by PKCg and VGLUT1) convey volitional motor commands from the cortex.Sensory inputs from the skin and muscles (labelled by VGLUT1 but not PKCg).Studying the development of CST and sensory inputs to dI3 INs will provide unique insights into how the nervous system matures to control movements through the cortical control of reflexes.My aim is to determine the number of sensory and CST inputs to dI3 INs.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.001 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.001 | 0.002 |
| Insufficient payload (model declined to judge) | 0.006 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".