Cytogenetic Findings on 11,451 Cases of Amniocentesis in Hanoi, Vietnam
Bibliographic record
Abstract
Since the 1960s, amniocentesis has become a routine procedure performed in prenatal diagnostic clinics. This study aims to depict the results of amniocentesis, the frequency of chromosomal abnormality and emphasize on amniocentesis indications. A retrospective study was conducted on 11,451 cases who were referred to the Prenatal Diagnosis Center, the National Hospital of Obstetrics and Gynecology, Hanoi, Vietnam from 2012 to 2016. The rate of chromosomal abnormality was 6.7%. The chromosomal aberration in the group with mother or father carrying balanced parental translocations accounted for the highest rate of 22.0%. Triploidy was 1.2%, autosomal chromosome aberration was 59.7%, sex chromosome was 8.3%, and structural rearrangements was 30.8%. Trisomy 21 was the most frequent disorder founded in abnormal ultrasound findings (47.4%), following by the advanced maternal age (44.1%). The large sample size of this study provided reliable evidence to support the development of prenatal counseling and pregnancy management programs.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".