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Inflammatory Bowel Disease Susceptibility Gene <i>C1ORF106</i> Regulates Intestinal Epithelial Permeability

2018· article· en· W2805831701 on OpenAlexaff
Paolo Manzanillo, Maria L. Mouchess, Naruhisa Ota, Bingbing Dai, Ryan Ichikawa, Arthur Wüster, Benjamin Haley, Gabriela Alvarado, Youngsu Kwon, Roger Caothien, Meron Roose-Girma, Søren Warming, Brent S. McKenzie, Mary Keir, Alexis Scherl, Wenjun Ouyang, Tangsheng Yi

Bibliographic record

VenueImmunoHorizons · 2018
Typearticle
Languageen
FieldMedicine
TopicHelicobacter pylori-related gastroenterology studies
Canadian institutionsDiscovery Centre
FundersGenentech
KeywordsIntestinal permeabilityProinflammatory cytokineInflammatory bowel diseaseTight junctionEpitheliumIntestinal epitheliumTumor necrosis factor alphaInflammationImmunologyDiarrheaCell biologyBiologyDiseaseMedicinePathology

Abstract

fetched live from OpenAlex

OpenAlex records an abstract for this work, but it could not be fetched just now.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.121
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.002
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.260
Teacher spread0.247 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations17
Published2018
Admission routes1
Has abstractyes

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