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Record W2806303726 · doi:10.1093/glycob/cwx089

Ten years of CAZypedia: a living encyclopedia of carbohydrate-active enzymes

2017· article· en· W2806303726 on OpenAlexafffund

Bibliographic record

VenueGlycobiology · 2017
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicEnzyme Production and Characterization
Canadian institutionsAgriculture and Agri-Food Canada
FundersAgriculture and Agri-Food CanadaGoddard Space Flight CenterUniversity of the RyukyusNatural Sciences and Engineering Research Council of CanadaNorges Miljø- og Biovitenskapelige UniversitetOulun YliopistoHokkaido UniversityUniversidad de ZaragozaDanmarks Tekniske UniversitetCentre National de la Recherche ScientifiqueNuclear PhysicsUniversity of WaterlooSveriges LantbruksuniversitetRIKENTokyo University of AgricultureSimon Fraser UniversityUniversity of LethbridgeKU LeuvenAalto-YliopistoUniversity of St AndrewsUniversiteit UtrechtRijksuniversiteit GroningenUniversity of LeedsWilfrid Laurier UniversitySlovenská Akadémia ViedKungliga Tekniska HögskolanPennsylvania State UniversityWeizmann Institute of ScienceItä-Suomen YliopistoBiotechnology and Biological Sciences Research CouncilInstitut National de la Recherche AgronomiqueUniversité de SherbrookeNational Institute of Advanced Industrial Science and TechnologyIowa State UniversityQueen Mary University of LondonNewcastle UniversityKindai UniversityUniversiteit GentUniversity of PennsylvaniaTokyo University of Agriculture and TechnologyKagoshima UniversityAkita Prefectural UniversityU.S. Department of Agriculture
KeywordsEncyclopediaCarbohydrateEnzymeChemistryBiochemistryLibrary scienceComputer science

Abstract

fetched live from OpenAlex

CAZypedia was initiated in 2007 to create a comprehensive, living encyclopedia of the carbohydrate-active enzymes (CAZymes) and associated carbohydrate-binding modules involved in the synthesis, modification and degradation of complex carbohydrates. CAZypedia is closely connected with the actively curated CAZy database, which provides a sequence-based foundation for the biochemical, mechanistic and structural characterization of these diverse proteins. Now celebrating its 10th anniversary online, CAZypedia is a successful example of dynamic, community-driven and expert-based biocuration. CAZypedia is an open-access resource available at URL http://www.cazypedia.org.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.007
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.016
Threshold uncertainty score0.054

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.007
Meta-epidemiology (narrow)0.0020.001
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0100.013
Science and technology studies0.0010.001
Scholarly communication0.0070.007
Open science0.0020.005
Research integrity0.0010.004
Insufficient payload (model declined to judge)0.0160.017

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.243
Teacher spread0.235 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations217
Published2017
Admission routes2
Has abstractyes

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