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Record W2806779311 · doi:10.3899/jrheum.171296

Polyserositis in a Patient with Active Systemic Lupus Erythematosus: A Case of Pseudo-pseudo Meigs Syndrome

2018· letter· en· W2806779311 on OpenAlexvenueno aff
Evangelia Zampeli, Fotini N. Skopouli, Haralampos Μ. Moutsopoulos

Bibliographic record

VenueThe Journal of Rheumatology · 2018
Typeletter
Languageen
FieldMedicine
TopicPericarditis and Cardiac Tamponade
Canadian institutionsnot available
Fundersnot available
KeywordsMedicinePericardial effusionLivedo reticularisHydroxychloroquineMeigs' syndromeSerositisPleural effusionAnti-nuclear antibodyInternal medicineSurgeryArthritisDermatologyGastroenterologyAutoantibodyDiseaseImmunology

Abstract

fetched live from OpenAlex

A 40-year-old woman was diagnosed with systemic lupus erythematosus (SLE) 10 years ago, manifesting with edematous hands, Raynaud phenomenon, livedo reticularis, arthralgias/arthritis of hand joints, and lymphadenopathy, without renal involvement. Laboratory and serological findings included chronic disease anemia, leukopenia, and diffuse hypergammaglobulinemia; positive antinuclear, anti-Sm, anti-Ro (Ro52 and Ro60), and increased anti-dsDNA antibodies; and hypocomplementemia. For the last 2 years, she was in remission under methylprednisolone 4 mg/day, azathioprine 100 mg/day, and hydroxychloroquine 200 mg/day. Two months before presentation, feeling inundated by the chronicity of her disease and treatment, she discontinued all medication. Upon presentation, she was unwell and dyspneic, and had intense livedo of lower extremities, Raynaud phenomenon, edematous hands with arthritis, and a distended abdomen. Breathing sounds of the left lung base were reduced. There was no pericardial friction rub or pulsus paradoxus, and echocardiography revealed a nonhemodynamically relevant pericardial effusion. Chest and abdominal computed tomography showed, in addition to the pericardial effusion, a unilateral pleural effusion (Figure 1A) and massive ascites (Figure 1B). Remarkable laboratory tests included elevated C-reactive protein [CRP; 30 mg/l, normal value (nv) < 5 mg/l], diffuse … Address correspondence to Dr. E. Zampeli, Institute for Autoimmune Systemic and Neurological Disorders, M. Asias 75, 11527, Athens, Greece. E-mail: zampelieva{at}gmail.com

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.556
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0030.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.232
Teacher spread0.224 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations20
Published2018
Admission routes1
Has abstractyes

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