Functionalized polymeric membrane with aquaporin using click chemistry for water purification application
Bibliographic record
Abstract
ABSTRACT A new type of aquaporin‐based biomimetic water purification membrane is fabricated using a propargyl functionalized β‐sheet peptide (FBP1). FBP1 is demonstrated to bind to aquaporin and form a stable protein–peptide complex in aqueous solution, as well as covalently conjugate with azide group. Substrate starting material, polysulfone (PSU), is modified with ∼1.05 azide group per repeating unit and casted into a thin film substrate with appropriate pore size structure using non‐solvent induced phase separation technique. Protein–peptide complex then is clicked onto the substrate using an in‐house built circulating system. The successful immobilization is verified by surface chemical composition analysis and surface morphology analysis. The preliminary salt rejection results show salt rejection improvement from 5% of control membrane to 12.5%. We thus demonstrate a promising method to conjugate a thin layer of membrane protein onto polymeric substrate and well maintain the functionality of membrane proteins. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018 , 135 , 46678.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".