Lesser Severity of Recurrent Takotsubo Cardiomyopathy While Taking Angiotensin II Receptor Blocker and Beta Blocker
Bibliographic record
Abstract
Takotsubo cardiomyopathy (TC) is characterized by transient systolic and diastolic dysfunction, ventricular wall motion abnormalities and troponin elevation. The most common presenting symptoms are acute chest pain and dyspnea. The etiology is unknown but believed to be related to a surge in catecholamines as it is commonly associated with a preceding physical or emotional stress. Due to the lack of specific treatment, recurrence occurs in 2-12% of patients per year. We present a case of a patient with TC subsequently treated with an angiotensin II receptor blocker (ARB) and beta-adrenergic blocker (beta-blocker). A repeat TC episode 4 months later showed less severely abnormal cardiac enzymes, echocardiogram and overall hospital course. Because our patient experienced a classic episode of TC and a recurrent episode with milder symptoms and lower troponins, we hypothesize her medication regimen was a contributing factor to the milder manifestation of this cardiac syndrome. J Med Cases. 2018;9(7):201-203 doi: https://doi.org/10.14740/jmc3079w
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".