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Record W2849678145 · doi:10.1080/07060661.2018.1498394

Detection of<i>Diplodia corticola</i>spores in Ontario and Québec based on High Throughput Sequencing (HTS) methods

2018· article· en· W2849678145 on OpenAlexaffvenueabout
Jean A. Bérubé, Patrick Gagné, Julien Ponchart, Emilie Tremblay, Guillaume J. Bilodeau

Bibliographic record

VenueCanadian Journal of Plant Pathology · 2018
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicPlant Pathogens and Fungal Diseases
Canadian institutionsCanadian Food Inspection AgencyUniversité LavalNatural Resources Canada
Fundersnot available
KeywordsSporeBiologyDNA sequencingRibosomal DNABiological dispersalShotgun sequencingIon semiconductor sequencingBotanyPhylogenetic treeGeneticsDNAGene

Abstract

fetched live from OpenAlex

A total of 252 aerial spore samples from the provinces of Quebec and Ontario were obtained during an extensive research programme focusing on aerobiology of fungal spores. Samples were collected on 95 sticky rods from rotary arm spore collectors and 157 filters from passive rain collectors. DNA from samples was PCR-amplified for fungal ribosomal ITS and sequenced using High Throughput Sequencing (HTS) methods. After bioinformatics analysis of DNA sequences, the presence of Diplodia corticola, an emerging tree pathogen in North America, was observed. In total, 313 DNA sequence reads from aerial spores of D. corticola were found in the Illumina data set, and 199 DNA sequence reads were obtained from the Ion Torrent data set. DNA of D. corticola was found in 16 of the 32 sampled sites, always less than 10 reads per site, with the exception of three sites – Quebec City, Aylmer and Ottawa – where 287, 125 and 73 DNA reads, respectively, were detected. This is not a first report of the presence of D. corticola causing a tree disease in Canada as symptomatic trees have not been identified. Typically, like many other species of the Botryosphaeriaceae, this fungal pathogen is believed to be an opportunistic plant endophyte capable of living asymptomatically for several years before showing up as a pathogen when conducive conditions arise. Its presence as singletons in nearly half the sampled sites in Quebec and Ontario may be the result of long-distance spore dispersal originating from known infected sites in Massachusetts, Maine and other unknown sites in the north-eastern USA. However, its much higher read counts in three sites may indicate the possibility of a few trees being asymptomatically infected and spreading conidia locally.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.015
Threshold uncertainty score0.109

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.002
Science and technology studies0.0020.001
Scholarly communication0.0020.000
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.234
Teacher spread0.219 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations22
Published2018
Admission routes3
Has abstractyes

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