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Record W28592287 · doi:10.1186/s12954-017-0160-3

Hormonal responses and pregnancy outcomes after five-day ovulation synchronization and presynchronization programs in lactating dairy cows

2014· dissertation· en· W28592287 on OpenAlexfundno aff
Stephanie Leeann Pulley

Bibliographic record

VenueHarm Reduction Journal · 2014
Typedissertation
Languageen
FieldAgricultural and Biological Sciences
TopicReproductive Physiology in Livestock
Canadian institutionsnot available
FundersBritish Columbia Centre for Disease Control
KeywordsOvulationPregnancyInternal medicineMedicineEstrous cycleEndocrinologyArtificial inseminationGonadotropin-releasing hormoneHormoneAnimal scienceBiologyLuteinizing hormone

Abstract

fetched live from OpenAlex

Two experiments assessed pregnancy outcomes (pregnancy per AI; P/AI) after 5-d Ovsynch-56 Resynch (RES; GnRH injection 5 d before [GnRH-1; d 0] and 56 h (GnRH-2) after the last PGF2α [PGF] injection on d 6 given 24 h after first PGF injection on d 5, and TAI on d 8) with and without a 5-d progesterone insert.In Exp. 1, only 76% of 1,023 nonpregnant cows enrolled on d 34 post-AI had high (≥1 ng/mL) progesterone.The RES-CIDR cows with low progesterone at treatment initiation had greater P/AI than RES-CON (37.7 vs. 29.4%),whereas RES-CIDR cows with high progesterone had lesser P/AI than RES-CON (27.4 vs. 34.3%)suggesting that supplemental progesterone is progesterone-dependent.In Exp. 2, 381 cows were enrolled in similar treatments on d 31 with RES on d 41post-AI plus a third treatment including PG-3-G (Pre-PGF on d 31, Pre-GnRH on d 34, and RES on d 41.The P/AI was similar among treatments but was greater in cows starting RES on d 41 when progesterone was low (44%) than high (33%).Experiment 3 determined LH and ovulatory responses in cows enrolled in two treatments before AI: 1) Pre10 (n = 37): PGF-1 and PGF-2 given 14 d apart (Presynch); or PG3G(n = 33): PGF given concurrent with the PGF-2, 3 d before GnRH-1 followed in 7 d by Ovsynch [injection of GnRH (GnRH-2) 7 d before PGF (PGF-3) and GnRH-3 at either 56 or 72 h after PGF-3] that was initiated 10 d after PGF-2 for Pre10 or 7 d after GnRH-1 of PG3G.The GnRH-1 increased incidences of LH surges and ovulation in PG3G compared with Pre10.The LH in serum of Pre10 was greater than that of cows receiving PG3G after GnRH-2.Following GnRH-3, cows receiving GnRH at 72 h had increased incidence of spontaneous LH surges before GnRH-3.The P/AI for PG3G vs. Pre10 and for 56 vs. 72 h was similar, but the Pre10-72 h treatment combination was less than all other treatment combinations.Release of LH is protocol dependent and flexibility of GnRH timing is an advantage for PG3G before first-service TAI.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.009
Threshold uncertainty score0.017

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.263
Teacher spread0.241 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2014
Admission routes1
Has abstractyes

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