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Record W2888325165 · doi:10.1371/journal.pntd.0006712

Echinococcus in wild canids in Québec (Canada) and Maine (USA)

2018· article· en· W2888325165 on OpenAlexafffundabout
Janna M. Schurer, Émilie Bouchard, Ann Bryant, Sarah Revell, Grace J. Chavis, Anne Lichtenwalner, Emily Jenkins

Bibliographic record

VenuePLoS neglected tropical diseases · 2018
Typearticle
Languageen
FieldMedicine
TopicParasitic infections in humans and animals
Canadian institutionsUniversity of Saskatchewan
FundersNatural Sciences and Engineering Research Council of CanadaU.S. Fish and Wildlife ServiceCanadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of CanadaNational Center for Veterinary ParasitologyUniversities Space Research AssociationUniversity of Saskatchewan
KeywordsEchinococcus multilocularisBiologyWildlifeZoologyMitochondrial DNARange (aeronautics)MetacestodeEcologyEchinococcosisVeterinary medicineCestodaHelminthsGeneGenetics

Abstract

fetched live from OpenAlex

Zoonotic Echinococcus spp.cestodes (E.canadensis and E. multilocularis) infect domestic animals, wildlife, and people in regions of Canada and the USA.We recovered and quantified Echinococcus spp.cestodes from 22 of 307 intestinal tracts of wild canids (23 wolves, 100 coyotes, 184 red and arctic foxes) in the state of Maine and the province of Que ´bec.We identified the species and genotypes of three Echinococcus spp.cestodes per infected animal by sequencing mitochondrial DNA at two loci.We further confirmed the absence of E. multilocularis by extracting DNA from pools of all cestodes from each animal and running a duplex PCR capable of distinguishing the two species.We detected E. canadensis (G8 and G10), but not E. multilocularis, which is emerging as an important human and animal health concern in adjacent regions.Prevalence and median intensity of E. canadensis was higher in wolves (35%, 460) than coyotes (14%, 358).This parasite has historically been absent in Atlantic regions of North America, where suitable intermediate hosts, but not wolves, are present.Our study suggests that coyotes are serving as sylvatic definitive hosts for E. canadensis in Atlantic regions, and this may facilitate eastward range expansion of E. canadensis in the USA and Canada.As well, compared to wolves, coyotes are more likely to contaminate urban green spaces and peri-urban environments with zoonotic parasites. Author summaryEchinococcosis is a zoonosis caused by ingestion of tapeworm eggs in feces of wild or domestic canids (e.g.foxes, wolves, coyotes, and dogs).In North America, the number of new human echinococcosis cases reported annually is low; however, recent reports of these parasites in unusual presentations, in new locations, and in wildlife near urban areas have caused renewed interest by veterinary and human health professionals.In a crossborder collaboration, we examined the intestines of wolves (Canis lupus), coyotes (C.latrans) and foxes (Vulpes vulpes, V. lagopus) trapped in Que ´bec (Canada) and neighboring Maine (USA), using genetic tools to identify Echinococcus tapeworms.We did not detect E. multilocularis, a serious threat to human health that has recently emerged in

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.013
Threshold uncertainty score0.094

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.002
Science and technology studies0.0020.001
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.256
Teacher spread0.243 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations37
Published2018
Admission routes3
Has abstractyes

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