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Record W2888709840 · doi:10.1007/s00401-018-1898-8

Methylome analysis and whole-exome sequencing reveal that brain tumors associated with encephalocraniocutaneous lipomatosis are midline pilocytic astrocytomas

2018· letter· en· W2888709840 on OpenAlexafffund
Elvis Terci Valera, Melissa K. McConechy, Tenzin Gayden, Bárbara Rivera, David Jones, Andrea Wittmann, HyeRim Han, Eric Bareke, Hamid Nikbakht, Leonie G. Mikael, R.G.P. Queiroz, Veridiana Kiill Suazo, Ji Hoon Phi, Seung‐Ki Kim, Sung‐Hye Park, Raita Fukaya, Mi‐Sun Yum, Tae‐Sung Ko, Ricardo Santos de Oliveira, Hélio Rubens Machado, María Sol Brassesco, Antonio Carlos do Santos, Gustavo Novelino Simão, Leandra Náira Zambelli Ramalho, Luciano Neder, Carlos Alberto Scrideli, Luíz Gonzaga Tone, Jacek Majewski, Nada Jabado

Bibliographic record

VenueActa Neuropathologica · 2018
Typeletter
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetic and rare skin diseases.
Canadian institutionsMcGill University and Génome Québec Innovation CentreMcGill University Health CentreMcGill UniversityMcGill Genome Centre
FundersNational Cancer InstituteNational Institutes of HealthBrain Tumour CharityFundação de Amparo à Pesquisa do Estado de São PauloBanting Research FoundationCanadian Institutes of Health ResearchCoordenação de Aperfeiçoamento de Pessoal de Nível SuperiorAlex's Lemonade Stand Foundation for Childhood Cancer
KeywordsPilocytic astrocytomaLipomatosisExome sequencingExomePathologyAstrocytomaMedicineGlioblastomaBiologyGeneticsCancer researchMutationGene

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.586
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.001
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.015
GPT teacher head0.219
Teacher spread0.204 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations22
Published2018
Admission routes2
Has abstractno

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