5048Electrocardiographic and pathologic changes in young sudden death victims affected with arrhythmogenic cardiomyopathy: a clinic-pathology study
Bibliographic record
Abstract
Background: Arrhythmogenic cardiomyopathy (AC) is an inherited heart muscle disease at risk of ventricular arrhythmias and sudden death (SD) particularly in the young and athletes. AC is characterized by distinct morphologic, imaging and electrocardiographic (ECG) features, Purpose: To correlate the ECG changes with the morphologic findings as assessed by pathology study of the hearts of young SD victims affected by AC. Methods: Our series of young SD AC cases was searched for available ECG tracing. The presence and the site of negative T waves (precordial leads or infero-lateral), low QRS voltage or normal ECG were evaluated. The SD victims who performed competitive sports were further selected and analyzed according to pre- or post- updated AC diagnostic criteria (2000). Disease distribution in terms of right ventricular (RV), left dominant AC (LDAC) or bi-ventricular (BiV) involvement was assessed and correlated with ECG. Results: The ECG tracing was available in 49 SD victims (46 M, mean age 26 y). Involvement was RV in 7 (14%), LDAC in 12 (25%) and BiV in 29 (59%), while one had normal heart. ECG was negative in 20 (41%). Negative T waves were present in the precordial leads in 17 (35%) and in the infero-lateral leads in 8 (17%), and low voltages in 8 (17%).
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.004 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".