Fabrication of Novel Open-Cell Foams of Poly(ε-caprolactone)/Poly(lactic acid) Blends for Tissue-Engineering Scaffolds
Bibliographic record
Abstract
Poly(ε-caprolactone)/poly(lactic acid) (PCL/PLA) blends are very promising materials with biodegradable characteristics and tailorable performance for many applications. In this study, PCL and PLA were compounded at various ratios using a co-rotating twin-screw extruder. The morphology showed that they were immiscible but were dispersed well in each other. Very interesting and peculiar open-cell structures were obtained through a batch-foaming process. Interconnected holes with flexible PCL fibrils were created by high tensile stress during cell expansion, which contributed to the rapid diffusion of CO2. No cells collapsed at high foam expansion under all foaming conditions. Moreover, a small-diameter tubular PCL/PLA foamed scaffold had a tensile toe region of approximately 40%, which indicated a potential application for vascular tissue engineering. The human umbilical vein endothelial cells cultured on the surfaces of PCL/PLA blend foams showed high viability and migration.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".