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Record W2894399451 · doi:10.1167/18.10.362

fMRI adaptation reveals interactions between responses to achromatic and S-cone isolating stimuli across visual cortex

2018· article· en· W2894399451 on OpenAlexaff
Erin Goddard, Robert F. Hess, Kathy T. Mullen

Bibliographic record

VenueJournal of Vision · 2018
Typearticle
Languageen
FieldNeuroscience
TopicVisual perception and processing mechanisms
Canadian institutionsMcGill University
Fundersnot available
KeywordsStimulus (psychology)Achromatic lensVisual cortexNeurosciencePsychologySensory AdaptationSensory systemCognitive psychologyPhysicsOptics

Abstract

fetched live from OpenAlex

Introduction: We used fMRI adaptation to investigate cortical selectivity to S-cone isolating (BY) and achromatic (Ach) stimuli. Previous work (Mullen et al, EJN, 2015, doi: 10.1111/ejn.13090) shows that for red-green (RG) and Ach contrast, there is increasing RG color selectivity in the higher ventral areas, especially VO. Here we used a similar paradigm to test the selective of responses to BY/Ach stimuli. Methods: We measured BOLD adaptation (3T scanner, TR=3s, 1.5 or 3mm isovoxels) to BY/Ach stimulus pairs (n=12), using similar methods to Mullen et al 2015. Both adapting and test stimuli were sinewave counter-phasing rings (0.5cpd, 2Hz), presented in a counterbalanced block design of adapt/no adapt, test and fixation blocks, with 96 repeats/subject. We used standard retinotopic mapping and localisers to define 9 ROIs (V1, V2, V3, V3a/b, LO, hMT, hV4, VO1 and VO2) and analysed data using AFNI/SUMA. Results: Across visual cortex, we found robust adaptation for all adaptor/test stimulus combinations (BY/BY, Ach/Ach, BY/Ach and Ach/BY). Across the 9 ROIs there was no significant main effect of either test or adaptor stimulus, but there was a significant interaction between these effects (F(1,385) = 9.23, p< 0.01). Ach test stimuli have a greater signal loss following BY than Ach adaptation, while BY tests had similar signal loss for both adaptors. Interestingly, the interaction was in the opposite in direction to that expected, with greater cross-stimulus adaptation than within-stimulus adaptation. Conclusion: Our data suggest that the S-cone pathway has qualitatively different interactions with cortical responses to Ach contrast than to RG. Responses to BY and Ach contrast are unselective across the cortical areas tested, unlike previous results for RG/Ach stimuli. The cross-adaptation of S-cone isolating stimuli on achromatic responses reveals an unexpected non-linear effect that is not accounted for by conventional stimulus adaptation models. Meeting abstract presented at VSS 2018

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.109
GPT teacher head0.451
Teacher spread0.342 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2018
Admission routes1
Has abstractyes

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