Differences in cardiovascular health in ambulatory persons with cerebral palsy
Bibliographic record
Abstract
Physical activity has many health benefits, one of which is the health of the heart and blood vessels.People with cerebral palsy are at risk of developing unhealthy heart and blood vessels due to limitations in mobility reducing the amount of physical activity they can perform.We studied the differences in blood vessel health between people with cerebral palsy who walk without limitations compared with those who walk with limitations.The group who walk without limitations had better measures of vessel health, such as lower blood pressure, and engaged in more physical activity than those who walk with limitations.We recommend that healthcare providers measure blood pressure and discuss physical activity with people with cerebral palsy in order to help them maintain heart and blood vessel health.Objective: To compare cardiovascular health vari ables and physical activity levels of adolescents and adults with cerebral palsy who are Gross Motor Func tion Classification System (GMFCS) levels I and II.Methods: Eleven adolescents (mean age 13.1 (stan dard deviation (SD) 2.1) years) and 14 adults (mean age 31.7 (SD 10.4) years)) with cerebral palsy were included, grouped by their GMFCS level (level I (n = 12); level II (n = 13)).Assessments of cardio vascular health, body composition and physical acti vity levels were performed.Cardiovascular variables included resting blood pressure and carotid artery intima media thickness.Body composition included height, weight, body mass index, and waist circum ference.Physical activity was measured using acce lerometry.Results: Adjusting for age between GMFCS levels (GMFCS I mean 17.3 (SD 5.2); GMFCS II mean 29.3 (SD 14.1) years, p = 0.011), significant differences were evident for moderate-to-vigorous physical activity per day (GMFCS I median 45.8 (interquar tile range (IQR) 32.4-75.1);GMFCS II median 16.4 (IQR 13.0, 25.0) min/day, p = 0.011), height (GM FCS I mean 1.63 (SD 0.14); GMFCS II mean 1.56 (SD 0.12) m, p = 0.010), mean arterial pressure (GMFCS I mean 84.6 (SD 7.8); GMFCS II mean 89.4 (SD 8.5) mmHg, p = 0.030), and carotid artery intima media thickness (GMFCS I mean 0.431 (SD 0.06); GMFCS II mean 0.489 (SD 0.04), p = 0.026).Conclusion: Individuals with cerebral palsy who were GMFCS level I had lower mean arterial pres sure, thinner carotid artery intima media thickness, and engaged in a greater amount of moderate-tovigorous physical activity per day than those who were GMFCS level II.Clinicians should acknowled ge that ambulatory individuals with cerebral palsy could have differing cardiovascular health profiles and should monitor these cardiovascular variables and discuss physical activity during healthcare vi sits, regardless of age.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".