P17.03: Uterocervical angle measurement in the prediction of preterm birth in women presenting with threatened preterm labour
Bibliographic record
Abstract
To determine if uterocervical angle (UCA), compared with cervical length (CL), is an independent predictor of spontaneous preterm birth (SPTB) in women with threatened preterm labour (TPTL). This retrospective cohort study included women with live singleton gestations and intact membranes who had an episode of TPTL, underwent transvaginal ultrasonographic CL (TVUSCL) assessment between 16 wk-29 6/7wk, and delivered Jul2007-Dec2016. UCA was measured retrospectively on ultrasound images. The primary outcome was SPTB<34wk, with secondary outcomes including SPTB<37wk and neonatal morbidity. Univariate analysis was used to compare demographic characteristics. ROC curve was generated to determine the best cut-off for UCA. Multiple logistic regression(MLR) was performed calculating ORs and 95%CIs, to identify independent predictors for the outcomes of interest. 263 women underwent TVUSCL assessment, of whom 211(80.2%) had UCA measurement obtained. ROC curve found the best cut-off for UCA to be ≥125o. Women who delivered <34wk were more likely to have a history of SPTB(43.8% versus 12.3%, p=0.003), CL<2.5cm(62.5% versus 15.9%, p<0.0001) and UCA≥125o(62.5% versus 21.3%, p=0.002). MLR found the independent predictors of SPTB<34wk to be CL<2.5cm(OR 7.37,95%CI2.42-22.43, p<0.0001) and history of SPTB(OR 4.12,95%CI1.39-13.06, p=0.016). Independent predictors of SPTB<37wk included CL<2.5cm(OR 11.43,95%CI4.80-27.23, p<0.0001), history of SPTB(OR 3.07 95%CI1.07-8.84, p=0.038) and history of LEEP(OR 2.97,95%CI1.02-8.69, p=0.047). Independent predictors of neonatal morbidity were CL<2.5cm(OR 5.33,95%CI2.22-12.79, p<0.0001) and history of SPTB(OR 3.75,95%CI1.43-9.81, p=0.009). UCA was not an independent predictor in any of the models. Although a wide UCA≥125o in women with singleton gestations presenting with TPTL is associated with SPTB<34wk, it is not as good as CL in predicting SPTB<34k, <37wk or neonatal morbidity. Further research is needed to determine if this measurement is useful in other populations. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.005 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".