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Record W2900083938 · doi:10.3389/fninf.2018.00077

The CAMH Neuroinformatics Platform: A Hospital-Focused Brain-CODE Implementation

2018· article· en· W2900083938 on OpenAlexafffundabout
David Rotenberg, Qing Chang, Natalia Potapova, Andy Wang, Marcia Hon, Marcos Sanches, Nikola Bogetic, Nathan Frias, Tommy Liu, Brendan Behan, Rachad El-Badrawi, Stephen C. Strother, Susan Gilbert Evans, Jordan Mikkelsen, Tom Gee, Fan Dong, Stephen R. Arnott, Shuai Laing, Moyez Dharsee, Anthony L. Vaccarino, Mojib Javadi, Kenneth Evans, Damian Jankowicz

Bibliographic record

VenueFrontiers in Neuroinformatics · 2018
Typearticle
Languageen
FieldNeuroscience
TopicFunctional Brain Connectivity Studies
Canadian institutionsIndoc ResearchUniversity of TorontoPublic Health OntarioBaycrest HospitalOntario Brain InstituteCentre for Addiction and Mental Health
FundersCanada Foundation for InnovationGovernment of Ontario
KeywordsNeuroinformaticsStandardizationComputer scienceContext (archaeology)Data scienceAnalytics

Abstract

fetched live from OpenAlex

Understanding the human brain in both healthy function and in the context of psychiatric illness presents a formidable technical and analytic challenge for medical researchers. Multi-modal data, including medical imaging, molecular and clinical measures provide lenses through which the brain’s structure, function, expression and behavioral presentation can be studied. While directed integration of complementary information promises to accelerate discovery and identify cross-modal biomarkers for stratification, diagnosis and treatment, such approaches, require stringent data standardization and are often computationally demanding, compounded by increased data volumes, statistical power and sample size requirements. To realize the potential of multi-modal data integration toward the study of mental illness, the Center for Addiction and Mental Health (CAMH) constructed a centralized data capture, visualization and analytics environment – the CAMH Neuroinformatics Platform – based on the Ontario Brain Institute (OBI) Brain-CODE platform, enabling the curation of a standardized, consolidated psychiatric hospital-wide research dataset, directly coupled to high performance computing resources.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.007
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.212
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.007
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0010.001
Scholarly communication0.0000.002
Open science0.0010.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.273
Teacher spread0.250 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designNot applicable
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations12
Published2018
Admission routes3
Has abstractyes

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