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Record W2900083938 · doi:10.3389/fninf.2018.00077

The CAMH Neuroinformatics Platform: A Hospital-Focused Brain-CODE Implementation

2018· article· en· W2900083938 on OpenAlexafffundabout
David Rotenberg, Qing Chang, Natalia Potapova, Andy Wang, Marcia Hon, Marcos Sanches, Nikola Bogetic, Nathan Frias, Tommy Liu, Brendan Behan, Rachad El-Badrawi, Stephen C. Strother, Susan Gilbert Evans, Jordan Mikkelsen, Tom Gee, Fan Dong, Stephen R. Arnott, Shuai Laing, Moyez Dharsee, Anthony L. Vaccarino, Mojib Javadi, Kenneth Evans, Damian Jankowicz

Bibliographic record

VenueFrontiers in Neuroinformatics · 2018
Typearticle
Languageen
FieldNeuroscience
TopicFunctional Brain Connectivity Studies
Canadian institutionsIndoc ResearchUniversity of TorontoPublic Health OntarioBaycrest HospitalOntario Brain InstituteCentre for Addiction and Mental Health
FundersCanada Foundation for InnovationGovernment of Ontario
KeywordsNeuroinformaticsStandardizationComputer scienceContext (archaeology)Data scienceAnalytics

Abstract

fetched live from OpenAlex

Understanding the human brain in both healthy function and in the context of psychiatric illness presents a formidable technical and analytic challenge for medical researchers. Multi-modal data, including medical imaging, molecular and clinical measures provide lenses through which the brain’s structure, function, expression and behavioral presentation can be studied. While directed integration of complementary information promises to accelerate discovery and identify cross-modal biomarkers for stratification, diagnosis and treatment, such approaches, require stringent data standardization and are often computationally demanding, compounded by increased data volumes, statistical power and sample size requirements. To realize the potential of multi-modal data integration toward the study of mental illness, the Center for Addiction and Mental Health (CAMH) constructed a centralized data capture, visualization and analytics environment – the CAMH Neuroinformatics Platform – based on the Ontario Brain Institute (OBI) Brain-CODE platform, enabling the curation of a standardized, consolidated psychiatric hospital-wide research dataset, directly coupled to high performance computing resources.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.010
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.026
Threshold uncertainty score0.075

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.010
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0010.002
Science and technology studies0.0010.001
Scholarly communication0.0020.002
Open science0.0050.004
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0220.010

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.273
Teacher spread0.250 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations12
Published2018
Admission routes3
Has abstractyes

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