Psychosocial determinants of health related quality of life in chronic Inflammatory Bowel Disease (IBD)
Bibliographic record
Abstract
Background: IBD comprises the two chronic inflammatory disorders of the gastrointestinal tract, Crohn’s disease (CD) and ulcerative colitis (UC). IBD patients frequently experience psychological symptoms such as anxiety, depression and other impairments due to the complex interactions between the dysfunctional brain-gut axis. IBD patients report lower quality of life compared to age and sex-matched health controls. Aim: Current research demonstrates that some of the main determinants of health-related quality of life (HRQOL) in IBD include work disability, increased disease severity, number of relapses, biological treatment and hospitalization rate. Despite the established strong psychosocial component of IBD, there is limited data available on how psychosocial factors influence HRQOL in these patients. The goal of this study is to characterize some of the psychosocial variables that influence HRQOL in IBD. Methods: This study is an observational cohort of 93 IBD (59CD;34UC: 66 inactive, 27 active disease) patients attending McGill University Health Centre IBD clinic Patients completed several validated questionnaires relating to different psychosocial parameters. Data was analyzed using SPSS version 17.0 software. Results: Preliminary analyses of this patient population reveal statistically significant negative correlation between HRQOL and hospital anxiety (r=-0.299, p<0.05) as well as positive correlation between HRQOL and Generalized Self-Efficacy (r=0.557, p<0.05). Additionally, analyses of self-reported emotional intelligence (SREIT) in this population reveal significant correlation between SREIT and ability to adaptively cope with disease (r=0.435, p<0.01). Conclusion: Psychosocial factors related to self efficacy and EI are key determinants of HRQOL in IBD and are being defined further in a multivariate model
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.014 | 0.002 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".