5.3 CAROTID ARTERY STIFFNESS INCREASES THE RISK OF INCIDENT DEPRESSIVE SYMPTOMS: THE PARIS PROSPECTIVE STUDY 3
Bibliographic record
Abstract
Objective: The study aims to investigate the role of cardiorespiratory fitness as a mediator of the relationship between arterial stiffness and cognitive function in apparently healthy seniors.Methods: This is a cross-sectional study comprising 155 participants (75.5 Æ 6.5 years; 69.7% female).Arterial stiffness and cognitive function were assessed with carotid-femoral pulse wave velocity (cfPWV) (Sphygmo-Cor, AtCor Medical, Australia), and Montreal Cognitive Assessment (MoCA), respectively.Cardiorespiratory fitness was calculated using the 6-minute walk test.Simple mediation analysis with bootstrapped procedures was calculated with Hayes's PROCESS macro for SPSS.Results: After adjustments for gender and age, cardiorespiratory fitness significantly mediated the relationship between arterial stiffness and cognitive function (Indirect effectZ À0.229 [95% CI, À0.455 to À0.046]).Conclusion: The present findings suggest that cardiorespiratory fitness, independently of gender and age, is a mediator of the relationship between arterial stiffness and cognitive function.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.002 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.001 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.001 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.003 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".