5.3 CAROTID ARTERY STIFFNESS INCREASES THE RISK OF INCIDENT DEPRESSIVE SYMPTOMS: THE PARIS PROSPECTIVE STUDY 3
Bibliographic record
Abstract
Objective: The study aims to investigate the role of cardiorespiratory fitness as a mediator of the relationship between arterial stiffness and cognitive function in apparently healthy seniors.Methods: This is a cross-sectional study comprising 155 participants (75.5 AE 6.5 years; 69.7% female).Arterial stiffness and cognitive function were assessed with carotid-femoral pulse wave velocity (cfPWV) (Sphygmo-Cor, AtCor Medical, Australia), and Montreal Cognitive Assessment (MoCA), respectively.Cardiorespiratory fitness was calculated using the 6-minute walk test.Simple mediation analysis with bootstrapped procedures was calculated with Hayes's PROCESS macro for SPSS.Results: After adjustments for gender and age, cardiorespiratory fitness significantly mediated the relationship between arterial stiffness and cognitive function (Indirect effectZ À0.229 [95% CI, À0.455 to À0.046]). Conclusion:The present findings suggest that cardiorespiratory fitness, independently of gender and age, is a mediator of the relationship between arterial stiffness and cognitive function.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.003 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".