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Record W2904404882 · doi:10.1093/jas/sky404.663

185 The effect of reduced dietary glycine and supplemental threonine on growth performance and collagen content in skin of pigs fed low crude protein diets.

2018· article· en· W2904404882 on OpenAlexaff
Kátia de Pádua Silva, Wilfredo D Mansilla, Anna K. Shoveller, John K Htoo, J.P. Cant, Cornelis de Lange, L. Huber

Bibliographic record

VenueJournal of Animal Science · 2018
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicAnimal Nutrition and Physiology
Canadian institutionsUniversity of Guelph
Fundersnot available
KeywordsAnimal scienceThreonineGlycineBiologyDietary proteinChemistryFood scienceAmino acidBiochemistryEnzyme

Abstract

fetched live from OpenAlex

Thirty-five barrows (BW=15.1 ± 2.72 kg) were used to determine the effect of supplementing dietary Thr above estimated requirements on pig growth and skin collagen abundance when fed low-CP low-Gly diets. Pigs were randomly assigned to 1 of 5 dietary treatments: 1) Control, semi-purified diet that met EAA requirements (CON; 12.1% CP as-fed); the final proportion of NEAA was similar to that found in whole-body protein. The remaining diets were formulated by reducing Gly and Ser content to 60 and 20%, respectively, of CON and supplementing with either Glu or Thr at 2 levels each, to maintain similar CP concentrations: For diets 2 and 3, Thr was included at 1.59% (LT) or 2.34% (HT) at the expense of the NEAA mix. For diets 4 and 5, Glu was included at 3.47% (LG) or 4.64% (HG) at the expense of the NEAA mix. Pigs were fed at 2.8 × estimated ME requirements for maintenance in 3 equal meals per day over a 21-day experimental period. At slaughter, skin samples were collected for collagen analysis. All statistical analyses were determined using Proc GLIMMIX. There was no difference in initial or final BW. Overall, ADG for pigs fed diets supplemented with Glu (378g/d) was greater than those fed diets supplemented with Thr (359 ± 9.45g/d; P=0.041). Feed efficiency for pigs supplemented with Glu (0.431) was greater than diets supplemented with Thr (0.411 ± 0.01; P=0.074). Pigs fed diets supplemented with LG, HG and HT had reduced skin collagen content compared to CON (P<0.05), but collagen content was not different between pigs fed LT versus CON diets. Diets supplemented with Thr decreased performance by partitioning away from protein synthesis towards collagen production. Supplementing reduced-CP diets with 1.59% Thr can maintain normal skin collagen content. NEAA supply should be considered when formulating low CP diets beyond effects on growth performance.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.001
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.020
GPT teacher head0.244
Teacher spread0.224 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2018
Admission routes1
Has abstractyes

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