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P6544All you need is LE: utility of an abbreviated LACE score in predicting 30-day outcomes among patients hospitalized for Heart Failure (HF)

2018· article· en· W2904498131 on OpenAlexaffabout
Harriette G.C. Van Spall, S F Lee, Tauben Averbuch, Urun Erbas Oz, Manish Maingi, Michael Heffernan, Peter R. Mitoff, Michael C. Tjandrawidjaja, Mohammad I. Zia, K Simek, Liane Porepa, Mohamed Panju, Dennis T. Ko, Stuart J. Connolly

Bibliographic record

VenueEuropean Heart Journal · 2018
Typearticle
Languageen
FieldMedicine
TopicHeart Failure Treatment and Management
Canadian institutionsUniversity of TorontoSouthlake Regional Health CenterSt Joseph's Health CentreHalTechInstitute for Clinical Evaluative SciencesWilliam Osler Health SystemPopulation Health Research InstituteTrillium Health CentreMcMaster University
Fundersnot available
KeywordsMedicineHeart failureInternal medicineCardiologyEmergency medicineIntensive care medicine

Abstract

fetched live from OpenAlex

Background: Length of stay, Acuity, Comorbidities, and Emergency department (ED) visits (LACE) can predict 30-day clinical outcomes when measured at the point of care (POC) in patients hospitalized for HF. However Comorbidities (C) are difficult to score and most patients likely present with high Acuity (A). Purpose: To determine whether an abbreviated LACE score, based only on Length of stay and number of ED visits in the prior 6 months (LE), can reliably predict 30-day readmission and 30-day composite readmission/death when used at the POC in patients hospitalized for HF. Methods: This is a sub-study of the Patient-Centered Care Transitions in HF (PACT-HF) pragmatic stepped wedge cluster randomized trial, which implemented transitional care services for HF across 10 hospitals in Canada. We included patients hospitalized for HF and discharged alive. We measured LACE and LE at the POC, and obtained 30-day clinical outcomes via linkages to administrative databases. We used log-binomial regression models with either LACE or LE as the predictor and either 30-day all-cause readmission or 30-day composite all-cause readmission/death as the outcome. We assessed risk with risk ratios (RR) and 95% confidence intervals (CI); model discrimination with C-statistic; and model calibration with a Hosmer-Lemeshow test. We adjusted all models for PACT-HF services received, and internally validated the models using bootstrapping.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.008
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.010
Threshold uncertainty score0.019

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0030.008
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.032
GPT teacher head0.297
Teacher spread0.265 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2018
Admission routes2
Has abstractyes

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