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Record W2907318817 · doi:10.3201/eid2502.180771

Lyme Disease Emergence after Invasion of the Blacklegged Tick,<i>Ixodes scapularis</i>, Ontario, Canada, 2010–2016

2019· article· en· W2907318817 on OpenAlexfundaboutno aff
Manisha A. Kulkarni, Isha Narula, Andreea M. Slatculescu, Curtis Russell

Bibliographic record

VenueEmerging infectious diseases · 2019
Typearticle
Languageen
FieldImmunology and Microbiology
TopicVector-borne infectious diseases
Canadian institutionsnot available
FundersCanadian Institutes of Health Research
KeywordsIxodes scapularisLyme diseaseIxodesBorrelia burgdorferiTickTick-borne diseaseIncidence (geometry)BiologyVirologyMedicineIxodidaeImmunologyAntibody

Abstract

fetched live from OpenAlex

Analysis of surveillance data for 2010-2016 in eastern Ontario, Canada, demonstrates the rapid northward spread of Ixodes scapularis ticks and Borrelia burgdorferi, followed by increasing human Lyme disease incidence.Most spread occurred during 2011-2013.Continued monitoring is essential to identify emerging risk areas in this region.L yme disease (LD) is the most reported vectorborne dis- ease in North America, where it is caused by Borrelia burgdorferi sensu stricto and principally transmitted by the blacklegged tick (Ixodes scapularis) (1).With northward expansion of I. scapularis tick populations from endemic areas in the United States, LD is rapidly emerging in parts of central and eastern Canada (2-4).Although several studies have mapped blacklegged tick populations across Canada and developed models to predict future spread of ticks and LD risk (2,3), little is known about the extent of human LD in relation to tick vector distributions at a fine geographic scale.We examined spatiotemporal trends in the occurrence and expansion of I. scapularis ticks, B. burgdorferi-infected ticks, and human LD cases over a 7-year period to elucidate the process of LD emergence in eastern Ontario, Canada. The StudyOur study included 3 public health units in eastern Ontario, Canada: Kingston, Frontenac, and Lennox and Addington (KFL); Leeds, Grenville, and Lanark (LGL); and Ottawa.This region spans from the St. Lawrence River in the south to the Ottawa River in the north, and has several major population centers, including Kingston (2016 population 123,798) and Ottawa (2016 population 934,243) (5).The region is largely characterized by mixed deciduous forest and agricultural land use.We used data from the Integrated Public Health Information System database to identify human LD cases

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.023
Threshold uncertainty score0.164

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.002
Science and technology studies0.0010.001
Scholarly communication0.0010.000
Open science0.0010.001
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.004
GPT teacher head0.192
Teacher spread0.188 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations47
Published2019
Admission routes2
Has abstractyes

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