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Indications for thrombectomy in acute ischemic stroke from emergent large vessel occlusion (ELVO): report of the SNIS Standards and Guidelines Committee

2019· article· en· W2907594198 on OpenAlexaff
Maxim Mokin, Sameer A. Ansari, Ryan McTaggart, Ketan R. Bulsara, Mayank Goyal, Michael Chen, Justin F. Fraser

Bibliographic record

VenueJournal of NeuroInterventional Surgery · 2019
Typearticle
Languageen
FieldMedicine
TopicAcute Ischemic Stroke Management
Canadian institutionsUniversity of Calgary
Fundersnot available
KeywordsMedicineSolitaire Cryptographic AlgorithmStroke (engine)Randomized controlled trialStentAcute strokeSurgeryEndovascular treatmentOcclusionRadiologyIschemic strokeInternal medicineIschemiaModified Rankin ScaleAneurysm

Abstract

fetched live from OpenAlex

Table 1 Randomized trials and registries of modern approaches to thrombectomy Trial no of patients, total/Ia (when applicable) lVo location Time window for thrombectomy, hours Stroke severity (nIhSS score) Imaging criteria Treatment groups mrS score=0-2 at 90 days Randomized trials: Endovascular vs medical MR CLEAN 8 500/223 ICA, M1, M2, A1, A2 0-6 ≥2 No limit Endovascular arm: stent retrievers in 97% of IA cases, 87% of IA-treated patients received IV rtPA first.Control arm: IV rtPA in 91% of patients Endovascular group: 33% Control group: 19% NNT=7.1 ESCAPE 13 215/165 ICA, M1, both (all) M2s 0-12 'Disabling' symptoms but no strict NIHSS limit CT ASPECTS 6-10, moderate-to-good collateral status on mCTA Endovascular arm: stent retrievers in 86% of all IA cases.73% of IA-treated patients received IV rtPA first Control arm: IV rtPA in 79% of patients Endovascular group: 53% Control group: 29% NNT=4.2EXTEND-IA 9 70/35 ICA, M1, M2 0-6 No limit CTP/MRP core <70 mL Endovascular arm: IV rtPA plus Solitaire stent retriever in all IA cases.Control arm: IV rtPA in all Endovascular group: 71% NNT=3.2SWIFT PRIME 10 196/98 ICA, M1 0-6 8-29 CTP/MRP core ≤50 mL, CT/MRI ASPECTS 6-10 Endovascular arm: IV rtPA plus Solitaire stent retriever in all IA cases.Control arm: IV rtPA in all Endovascular group: 60% Control group: 35% NNT=4

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.096
metaresearch head score (Gemma)0.085
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.096
Threshold uncertainty score0.508

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0960.085
Meta-epidemiology (narrow)0.0020.002
Meta-epidemiology (broad)0.0070.008
Bibliometrics0.0060.007
Science and technology studies0.0020.002
Scholarly communication0.0060.002
Open science0.0060.002
Research integrity0.0060.008
Insufficient payload (model declined to judge)0.0040.004

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.031
GPT teacher head0.333
Teacher spread0.302 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations183
Published2019
Admission routes1
Has abstractyes

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