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Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk

2019· review· en· 2,526 citations· W2908002252 on OpenAlex· 10.1038/s41588-018-0311-9

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

No Canadian affiliation. An affiliation-only frame — the usual design — would never have seen this work. It is one of the works that make the case for inverting the frame.

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Nature Genetics
Topic
Genetic Associations and Epidemiology
Field
Biochemistry, Genetics and Molecular Biology
Canadian institutions
Funders
National Institute of Neurological Disorders and StrokeNational Institute on Deafness and Other Communication DisordersNational Institute of Mental HealthNational Heart, Lung, and Blood InstituteMedical Research CouncilNational Institute of General Medical SciencesCentre hospitalier régional universitaire de LilleNasjonalforeningen for FolkehelsenKarl-Franzens-Universität GrazVrije Universiteit AmsterdamErasmus Medisch CentrumNorges ForskningsrådHjartaverndNational Institutes of HealthÖsterreichische ForschungsförderungsgesellschaftAustrian Science FundEU Joint Programme – Neurodegenerative Disease ResearchInstitut National de la Santé et de la Recherche MédicaleUniversité de LilleEuropean CommissionMedizinische Universität GrazOesterreichische NationalbankAlzheimer's AssociationUniversity of TorontoCase Western Reserve UniversityEuropean Federation of Pharmaceutical Industries and AssociationsBundesministerium für Bildung und ForschungNational Institute on AgingNational Institute for Health and Care ResearchNederlandse Organisatie voor Wetenschappelijk OnderzoekWellcome TrustDevelopment of Innovative Strategies for a Transdisciplinary approach to ALZheimer's disease
Keywords
BiologyMendelian randomizationGenome-wide association studyDiseaseGeneticsAlzheimer's diseaseGenetic associationTREM2GeneGenomeSingle-nucleotide polymorphismImmune systemGenetic variantsGenotypeMedicineInternal medicine
Has abstract in OpenAlex
no