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Record W2910575557

The impact of insite, North America's first supervised injection facitity, and possible implementation in Massachusetts

2018· dissertation· en· W2910575557 on OpenAlexaboutno aff
Ryan Timothy Perera

Bibliographic record

VenueOpenBU/Boston University Institutional Repository (Boston University) · 2018
Typedissertation
Languageen
FieldMedicine
TopicIntramuscular injections and effects
Canadian institutionsnot available
Fundersnot available
KeywordsEnvironmental scienceEnvironmental planning
DOInot available

Abstract

fetched live from OpenAlex

The impact of the opioid crisis has been worsening in recent years. Opioid-related overdose deaths in the United States have reached 9.0 per 100,000 people and in Massachusetts the number is even worse at 17.3 per 100,000. People who inject drugs (PWID) are at high risk of overdose death, of superficial and deep tissue bacterial infections, and of chronic viral infections such as human immunodeficiency virus (HIV) and hepatitis C virus (HCV), which can be transmitted through shared injection equipment. Although abstinence from substances is the best way to avoid these outcomes, the complicated nature of substance use disorder (SUD) means that not everyone will be able to stop substance use at any given time. The concept of harm reduction is based on engaging PWID who are not ready or able to stop substance use, to reduce the frequency of adverse outcomes. One intervention supported by harm reductionists is medically supervised infection facilities (SIFs), which are locations where PWID may inject substances under medical supervision. People are provided with clean equipment and are monitored post-injection so that medical intervention can be provided in case of an overdose. Furthermore, people are able to access a variety of health services, including wound care, condom access, and referrals to SUD treatment. 
\nIn 2003, Insite in Vancouver, Canada became North America’s first legally sanctioned SIF. Research conducted since its opening has shown many positive benefits. Insite has been credited with the prevention of overdose deaths and the encouragement of safer injection practices both inside and outside of the facility. In addition, the facility has been shown to be an effective bridge to addiction treatment, particularly among higher risk PWID. The presence of Insite has also been associated with a reduction in public injections. Furthermore, Insite does not appear to increase the number of people who are actively injecting, nor does it serve as a location for people who are injecting drugs for the first time.
\n\tBecause of these benefits, there has been growing interest in establishing an SIF within the United States. Advocacy groups, including the Massachusetts Medical Society, have begun to press for one within Massachusetts. Moreover, the PWID community in Boston has expressed interest in taking advantage of the harm reduction benefits that an SIF can offer. Efforts to establish an SIF, however, face several barriers including state and federal drug laws and political opposition to such a facility. The stigma associated with SUD and the very idea of an SIF is an issue that must be addressed in order to bring this life saving tool to Massachusetts.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Science and technology studies
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.048
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0020.001
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.250
Teacher spread0.242 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2018
Admission routes1
Has abstractyes

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