Primitive Stem Cells in Adult Feline, Canine, Ovine, Caprine, Bovine, and Equine Peripheral Blood
Bibliographic record
Abstract
Stout et al. [1] reported the presence of primitive endogenous stem cells circulating within adult porcine peripheral blood.The current study was undertaken to determine whether similar primitive stem cells could be isolated from the peripheral blood of adult felines, canines, ovines, caprines, bovines, and equines.Adult cats, dogs, sheep, goats, cows and horses had their blood withdrawn following the guidelines of Fort Valley State University's IACUC.The blood was obtained by venipuncture and processed to obtain primitive stem cells.Cells were counted using 0.4% Trypan blue inclusion/exclusion analysis and stained with carcinoembryonic antigen-cell adhesion molecule-1 (CEA-CAM-1) antibody.Totipotent stem cells are both trypan blue and CEA-CAM-1 positive and < 2.0 microns in size; transitional-totipotent/pluripotent stem cells are both trypan blue and CEA-CAM-1 positive & negative and >2.0 to <6.0 microns in size; and pluripotent stem cells are both trypan blue and CEA-CAM-1 negative and 6-8 microns in size.The results show that TSCs, Tr-TSC/PSCs, and PSCs are circulating within the peripheral blood of all species examined.Studies are ongoing to address their functional significance during maintenance and healing.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".