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Record W2912402287 · doi:10.1093/ecco-jcc/jjy222.313

P189 Role of digestive wall’s ultrasound in the evaluation of post-surgical recurrence in Crohn's disease: correlation with endoscopic findings

2019· article· en· W2912402287 on OpenAlexaboutno aff
C Macedo, Elisa Gravito‐Soares, Marta Gravito‐Soares, A M Ferreira, Francisco Portela, Luís Tomé

Bibliographic record

VenueJournal of Crohn s and Colitis · 2019
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicInflammatory Bowel Disease
Canadian institutionsnot available
Fundersnot available
KeywordsCrohn's diseaseMedicineConcordanceUltrasoundColonoscopyGastroenterologyCalprotectinInternal medicineEndoscopyFaecal calprotectinDiseaseSurgeryInflammatory bowel diseaseRadiologyColorectal cancer

Abstract

fetched live from OpenAlex

Endoscopy remains the examination of choice in the evaluation of activity in Crohn's Disease (CD) after surgery (ADC-AS). However, digestive wall’s ultrasound (US-DW) may represent a non-invasive alternative. The objective of this study was to determine the diagnostic accuracy and concordance of this modality comparatively to endoscopy. Cross-sectional study, comprising a period of 14 months, carried out in patients with established CD and ileocaecal resection due to the disease. Performed US-DW (HI-VISION avius®, Tokyo, Japan) with linear probe B-mode/Doppler prior to ileocolonoscopy. US-DW and colonoscopy were performed on the same day by 2 specialists in gastroenterology dedicated to ultrasound and inflammatory bowel disease, in a double-blind mode. Collected demographic and clinical data [Harvey–Bradshaw index (HBI, remission: ≤4)], serological/faecal inflammatory parameters [leucocytes (4 < N <10 × 109 cells/l), C-reactive protein (≤0.5 mg/dl) faecal calprotectin (N <50 mg/kg), endoscopic (score Rutgeerts: remission < i2) and ultrasound [intestinal wall thickening (N ≤ 3 mm) and digestive wall’s vascularisation using the semi-quantitative score of Limberg (absent = 0, sparse = 1; moderate = 2; marked = 3)]. Included 39 patients (female: 64.1%, mean age: 43.5 ± 15.3 years). Surgery performed, on average, 5.3 ± 5.3 years after diagnosis. Mean post-surgery follow-up: 9.9 ± 6.9 years. Montreal classification: L1 61.5% (n = 24), L3 38.5% (n = 15), B1 and B2 28.2% (n = 11) and B3 43.6% (n = 17). Most of patients were in clinical remission (87.2%; n = 34) with mean HBI 2.1 ± 2.2. Twenty-two patients (56.4%) have normal inflammatory markers. US-DW (intestinal wall thickening> 3 mm and/or Limberg> 1) was abnormal in 61.5% (n = 24). Endoscopic remission (Rutgeerts

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.008

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0000.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0020.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.007
GPT teacher head0.250
Teacher spread0.244 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2019
Admission routes1
Has abstractyes

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