Part E, Porifera (Revised), vol. 5, Complete Volume
Bibliographic record
Abstract
Onychomycosis are superficial infections that are characterized by the destruction of the nail bed and adjacent tissues with yeast fungi as important etiological agents of these diseases. In this context, the present study aimed to conduct a literature review on the genus Candida, emphasizing the main species responsible for onychomycosis, according to their epidemiological, pathogenic, immunological, diagnostic and pharmacological treatment. The research was developed in an exploratory and qualitative way, with a database approach of scientific publications, repositories and indexers. In view of the articles, dissertations, books and theses, C. albicas, C. tropicalis and C. parapsilosis has been presented as the main species of the genus Candida from a clinical and epidemiological, for nail infections with diagnosis centered on the clinical history of the laboratory tests, and more recently, by the use of image recording. The infection and dissemination process in nails occurs when virulence factors (adhesion, biofilms, pleomorphism, toxins, hydrolytic enzymes and phenotypic variability), overlap the defensive factors (microbiota, mechanical barriers and immune system). The treatment is based on the eradication of the infecting microorganism and regression of signs and symptoms, with three main pharmacological strategies, topical treatment (amorolfilina, ciclopirox), oral treatment (itraconazole and fluconazole) and combination therapy, however resistance mechanisms have been associated with these drugs. Given the above, the information present in this research serves as an aid for the consolidation of clinical - epidemiological knowledge that focuses on onychomycosis, caused by fungi of the genus Candida, including students, health professionals, academics and all society.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; both teacher heads agree on what is shown here.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".