Bibliographic record
Abstract
Bilateral, end-stage, age-related macular degeneration (AMD) is a devastating condition of the eye. As the leading cause of blindness worldwide in the elderly, it leads to poor quality of life. While antivascular endothelium growth factor agents are used as front-line treatment for wet AMD, no current treatment exists for bilateral, end-stage AMD in Canada. The implantable miniature telescope (IMT), approved by the Food and Drug Administration in 2010, is a treatment option available for those over the age of 65 in the United States with stable severe to profound vision impairment (best-corrected visual acuity 20/160 to 20/800) caused by bilateral central scotomas associated with bilateral, end-stage AMD. Combining the fields of engineering and ophthalmology, intraocular implantation of the IMT provides improvements in patients’ functional vision and quality of life. As a relatively new treatment targeting the elderly, there are strict inclusion criteria as well as risks associated with the procedure. However, research and continuing development in this field is ongoing to minimize these risks.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".