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Record W2931133684 · doi:10.12968/coan.2019.24.4.212

Canine infective endocarditis

2019· article· en· W2931133684 on OpenAlexaboutno aff
Nora Romero‐Fernández, Valentina Palermo

Bibliographic record

VenueCompanion animal · 2019
Typearticle
Languageen
FieldMedicine
TopicInfective Endocarditis Diagnosis and Management
Canadian institutionsnot available
Fundersnot available
KeywordsInfective endocarditisEndocardiumEndocarditisBartonellaMedicineSepsisMicrobiologyBlood cultureBiologyAntibioticsImmunologyInternal medicine

Abstract

fetched live from OpenAlex

Canine infective endocarditis is defined as an infection of the endocardium, commonly involving one or more heart valves and leading to proliferative (vegetative) or erosive lesions. Prerequisites for development of infective endocarditis include endocardial damage, formation of a sterile vegetative lesion or coagulum, presence of bacteraemia and microorganism adherence to the coagulum. Predisposing factors include any that may facilitate meeting the prerequisites, including congenital heart disease, extra-oral infections and immunosuppression, amongst others. Large, male, middle-aged and purebred dogs may be overrepresented, in particular Labrador Retrievers, Golden Retrievers, Boxers and German Shepherd Dogs. Typically caused by bacteria, the most common isolates include Streptococcus spp., Staphylococcus spp., Gram-negative rods (particularly Escherichia coli) and Bartonella spp. Blood culture can have low sensitivity, with up to 70% of cultures being negative. Bartonella spp. are increasingly being recognised as a cause of culture-negative aortic infective endocarditis. The preferred method of diagnosis in vivo is echocardiography, with a reported sensitivity of 87.5%. The prognosis is guarded despite appropriate treatment, and some negative prognostic factors have been identified.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.010

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0000.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.265
Teacher spread0.254 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2019
Admission routes1
Has abstractyes

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