Dysbiosis of the Gut Microbiome in Lung Cancer
Why is this work in the frame?
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Full frame distilled prediction
Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
- Candidate categories
- none
- Consensus categories
- none
- Domain
- Candidate signal: noneConsensus signal: none
- Study design
- Candidate signal: Bench or experimentalConsensus signal: Bench or experimental
- Genre
- Candidate signal: EmpiricalConsensus signal: Empirical
- Teacher disagreement score
- 0.230
- Threshold uncertainty score
- 0.431
- Validation status
machine_predicted_unvalidated·codex-gemma-dda1882f352a
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
- Teacher spread
- 0.217 · how far apart the two teachers sit on this one work
- Validation status
score_only:v0-immature-baseline· verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it
Abstract
Dear Editor: We wish to submit a manuscript entitled “Dysbiosis of the gut microbiome in lung cancer ” to Frontiers in Cellular and Infection Microbiology, Microbiome in Health and Disease section, for your consideration to publish as a Research Article. In this study, we examined the gut microbiome between 30 lung cancer patients and 30 healthy controls via next generation sequencing of 16S rDNA to uncover potential biomarkers for early diagnosis and targeted intervention. Previous analyses of the microbe-lung cancer relationship have been focused on lung microbiome. To our knowledge, this is the first study of lung cancer from the perspective of gut microbiome. Our findings support the hypothesis of an lung cancer-specific compositional structure of gut bacterial populations. Our work suggests that the dysbiosis of the gut microbiome in lung cancer as reflected by reduced abundance of Actinobacteria and Bifidobacterium and elevated levels of Enterococcus had facilitated the development of lung cancer and may help develop novel strategies for early prevention and targeted intervention against lung cancer. The authors claim that none of the materials in the paper has been published or is under consideration for publication elsewhere. Thank you very much for your consideration and we look forward to hearing from you soon. Yours Sincerely He Zhuang and Shu-Lin Liu Genomics Research Center Harbin Medical University 157 Baojian Road Harbin, 150081 China
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
The record
- Venue
- Frontiers in Cellular and Infection Microbiology
- Topic
- Gut microbiota and health
- Field
- Biochemistry, Genetics and Molecular Biology
- Canadian institutions
- University of Calgary
- Funders
- not available
- Keywords
- DysbiosisMicrobiomeActinobacteriaBifidobacteriumBiologyGut floraLung cancerPhylumCancerPathogenesisColorectal cancerImmunologyMicrobiologyMedicineInternal medicineBacteria16S ribosomal RNABioinformaticsGeneticsLactobacillus
- Has abstract in OpenAlex
- yes