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Mapping Cortical and Subcortical Asymmetry in Obsessive-Compulsive Disorder: Findings From the ENIGMA Consortium
Xiangzhen Kong, Premika S.W. Boedhoe, Yoshinari Abe, Pino Alonso, Stephanie H. Ameis, Paul Arnold, Francesca Assogna, Justin T. Baker, Marcelo C. Batistuzzo, Francesco Benedetti, Irene Bollettini, Anushree Bose, Silvia Brem, Brian P. Brennan, Jan K. Buitelaar, Rosa Calvo, Yuqi Cheng, Kang Ik K. Cho, Sara Dallaspezia, Damiaan Denys, Benjamin A. Ely, Jamie D. Feusner, Jean‐Paul Fouché, Egill A. Friðgeirsson, David C. Glahn, Patricia Gruner, Deniz A. Gürsel, Tobias U. Hauser, Yoshiyuki Hirano, Marcelo Q. Hoexter, Hao Hu, Chaim Huyser, Anthony James, Fern Jaspers‐Fayer, Norbert Kathmann, Christian Kaufmann, Masaru Kuno, Gerd Kvale, Jun Soo Kwon, Luisa Lázaro, Yanni Liu, Christine Löchner, Paulo Marques, Rachel Marsh, Ignacio Martínez‐Zalacaín, David Mataix‐Cols, Sarah E. Medland, José M. Menchón, Luciano Minuzzi, Pedro Silva Moreira, Ástrid Morer, Akiko Nakagawa, Takashi Nakamae, Tomohiro Nakao, Janardhanan C. Narayanaswamy, Erika L. Nurmi, Joseph O’Neill, Jose Ángel Pariente, Chris Perriello, John Piacentini, Fabrizio Piras, Federica Piras, Christopher Pittenger, Y.C. Janardhan Reddy, Oana Georgiana Rus-Oswald, Yuki Sakai, João Ricardo Sato, H. Blair Simpson, Noam Soreni, Carles Soriano‐Mas, Gianfranco Spalletta, Emily Stern, Michael C. Stevens, S. Evelyn Stewart, Philip R. Szeszko, David F. Tolin, Aki Tsuchiyagaito, Daan van Rooij, Guido van Wingen, Ganesan Venkatasubramanian, Zhen Wang, Je‐Yeon Yun, Alan Anticevic, Nerisa Banaj, Núria Bargalló, Daniel Brandeis, Jan Buitelaar, Geraldo F. Busatto, Anna Calvo, Yuqi Cheng, Valentina Ciullo, Froukje E. de Vries, Stella J. de Wit, Erin W. Dickie, Renate Drechsler, Madalena Esteves, Andrea Falini, Yu Fang, Martijn Figee, Martine Fontaine, Geoff Hall, Sayo Hamatani, Gregory L. Hanna, Bjarne Hansen, Keisuke Ikari, Neda Jahanshad, Ricardo Magalhães, Yasutaka Masuda, Koji Matsumoto, James T. McCracken, Eurı́pedes Constantino Miguel, Jin Narumoto, Seiji Nishida, Sara Poletti, Y.C. Janardhan Reddy, Tim Jonas Reeß, Eiji Shimizu, Nuno Sousa, Gianfranco Spalletta, Jumpei Takahashi, Jinsong Tang, Anders Lillevik Thorsen, Ysbrand D. van der Werf, Dick J. Veltman, Daniela Vecchio, Susanne Walitza, Jian Xu, Xiufeng Xu, Kei Yamada, Tokiko Yoshida, Mojtaba Zarei, Qing Zhao, Cong Zhou, Paul M. Thompson, Dan J. Stein, Clyde Francks, Odile A. van den Heuvel
Bibliographic record
VenueBiological Psychiatry · 2019
Typereview
Languageen
FieldNeuroscience
TopicHemispheric Asymmetry in Neuroscience
Canadian institutionsUniversity of CalgaryLibin Cardiovascular Institute of AlbertaSt. Joseph’s Healthcare HamiltonUniversity of British ColumbiaHospital for Sick ChildrenBC Children's HospitalSickKids FoundationCentre for Addiction and Mental Health
FundersNational Center for Advancing Translational SciencesNational Institute of Mental HealthInstituto de Salud Carlos IIIJapan Society for the Promotion of ScienceSeventh Framework ProgrammeAlberta InnovatesNorges ForskningsrådMax-Planck-GesellschaftCanadian Institutes of Health ResearchBundesministerium für GesundheitFundação para a Ciência e a TecnologiaNational Alliance for Research on Schizophrenia and DepressionZonMwNational Natural Science Foundation of ChinaAgència de Gestió d'Ajuts Universitaris i de RecercaFundação de Amparo à Pesquisa do Estado de São PauloSchweizerischer Nationalfonds zur Förderung der Wissenschaftlichen ForschungOntario Mental Health FoundationNederlandse Organisatie voor Wetenschappelijk OnderzoekMinistry of Education, Culture, Sports, Science and TechnologyJacobs FoundationDeutsche ForschungsgemeinschaftJapan Agency for Medical Research and DevelopmentInternational OCD FoundationMichael Smith Health Research BCMinistero della SaluteOntario Brain InstituteBrain and Behavior Research FoundationFundació la Marató de TV3Helse VestGeneralitat de CatalunyaDepartment of Science and Technology, Ministry of Science and Technology, IndiaEli Lilly and CompanyEuropean Regional Development FundBundesministerium für Bildung und ForschungHartmann Müller-Stiftung für Medizinische ForschungMassachusetts General HospitalProvincial Health Services AuthorityWellcome TrustNew York State Office of Mental Health
KeywordsObsessive compulsivePsychologyAsymmetryNeurosciencePsychiatryPhysics
Abstract
OpenAlex records an abstract for this work, but it could not be fetched just now.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
metaresearch head score (Codex)0.009
metaresearch head score (Gemma)0.029
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Review · Consensus signal: none
Teacher disagreement score0.013
Threshold uncertainty score0.049
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.009 | 0.029 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.003 | 0.004 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.002 | 0.001 |
| Open science | 0.002 | 0.003 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
Opus teacher head0.097
GPT teacher head0.336
Teacher spread0.240 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreReview
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".
Quick stats
Citations118
Published2019
Admission routes2
Has abstractyes