Postpartum Venous Thromboembolism Prophylaxis May Cause More Harm than Benefit: A Critical Analysis of International Guidelines Through an Evidence-based Lens
Bibliographic record
Abstract
( BJOG . 2018;125:1109–1116) Prothrombotic hemostatic changes make pregnant and postpartum women logical targets for venous thromboembolism (VTE) prophylaxis. Most obstetric VTE guidelines recommend low–molecular-weight heparin (LMWH) for many postpartum women, including most delivering by cesarean. Although evidence is limited, a small subset of pregnant and postpartum women is at very high risk of VTE. Women with a personal history of VTE, potent thrombophilia, or prolonged immobilization usually receive and likely benefit from antenatal and postpartum LMWH prophylaxis. This perception of benefit has spread to women with more common risk factors, in whom the risk of VTE is lower.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.002 | 0.001 |
| Bibliometrics | 0.001 | 0.002 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.001 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".