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Record W2946744580 · doi:10.1093/jmp/jhab041

Reconciling Regulation with Scientific Autonomy in Dual-Use Research

2021· article· en· W2946744580 on OpenAlexaff
Nicholas G. Evans, Michael J. Selgelid, Robert Mark Simpson

Bibliographic record

VenueThe Journal of Medicine and Philosophy A Forum for Bioethics and Philosophy of Medicine · 2021
Typearticle
Languageen
FieldMedicine
TopicEthics in Clinical Research
Canadian institutionsMcMaster University
Fundersnot available
KeywordsAutonomyNormativeDual (grammatical number)Argument (complex analysis)Value (mathematics)CensorshipLaw and economicsEngineering ethicsEpistemologySociologyRisk analysis (engineering)Positive economicsPolitical scienceComputer scienceLawBusinessEconomicsMedicinePhilosophy

Abstract

fetched live from OpenAlex

In debates over the regulation of communication related to dual-use research, the risks that such communication creates must be weighed against against the value of scientific autonomy. The censorship of such communication seems justifiable in certain cases, given the potentially catastrophic applications of some dual-use research. This conclusion however, gives rise to another kind of danger: that regulators will use overly simplistic cost-benefit analysis to rationalize excessive regulation of scientific research. In response to this, we show how institutional design principles and normative frameworks from free speech theory can be used to help extend the argument for regulating dangerous dual-use research beyond overly simplistic cost-benefit reasoning, but without reverting to an implausibly absolutist view of scientific autonomy.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.241
metaresearch head score (Gemma)0.256
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Science and technology studies
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.992
Threshold uncertainty score0.935

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.2410.256
Meta-epidemiology (narrow)0.0010.002
Meta-epidemiology (broad)0.0020.002
Bibliometrics0.0030.002
Science and technology studies0.0080.100
Scholarly communication0.0170.024
Open science0.0060.023
Research integrity0.0230.023
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.638
GPT teacher head0.542
Teacher spread0.096 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designTheoretical or conceptual
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations12
Published2021
Admission routes1
Has abstractyes

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Same venueThe Journal of Medicine and Philosophy A Forum for Bioethics and Philosophy of MedicineSame topicEthics in Clinical ResearchFrench-language works237,207