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Record W2947090285 · doi:10.1186/s13104-019-4067-9

Comparing the EQ-5D-5L utility index based on value sets of different countries: impact on the interpretation of clinical study results

2019· article· en· W2947090285 on OpenAlexaboutno aff
Christoph Gerlinger, Luke Bamber, Friedhelm Leverkus, Carsten Schwenke, Claudia Haberland, G Schmidt, Jan Endrikat

Bibliographic record

VenueBMC Research Notes · 2019
Typearticle
Languageen
FieldEconomics, Econometrics and Finance
TopicHealth Systems, Economic Evaluations, Quality of Life
Canadian institutionsnot available
FundersBayer
KeywordsIndex (typography)Value (mathematics)MedicineMultinational corporationInterpretation (philosophy)StatisticsDemographyMathematicsEconomicsComputer scienceFinance

Abstract

fetched live from OpenAlex

OBJECTIVE: To compare the country-specific value sets of the EQ-5D-5L utility index and to evaluate the impact on the interpretation of clinical study results. Six country value sets from Canada, England, Japan, Korea, Netherlands and Uruguay were obtained from literature. In addition, ten crosswalk value sets were downloaded from the EuroQol.org website. RESULTS: For each of the 3125 possible health states the difference between the country with the highest index and the country with the lowest index was calculated. The median difference was 0.417 across the health states. When analyzing multinational clinical studies, country-specific value sets should be used to evaluate treatment effects. Additional country-specific analyses are needed.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.183
metaresearch head score (Gemma)0.445
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch
Consensus categoriesnone
DomainCandidate signal: Methods · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.817
Threshold uncertainty score0.965

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1830.445
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0030.005
Bibliometrics0.0060.011
Science and technology studies0.0010.002
Scholarly communication0.0060.003
Open science0.0020.004
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0030.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.740
GPT teacher head0.574
Teacher spread0.166 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designObservational
DomainMethods
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations107
Published2019
Admission routes1
Has abstractyes

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