Phenolics from canola crude extracts protect cells from oxidative stress
Bibliographic record
Abstract
Background: By-products of canola oil production are currently discarded or low value commodities.This study investigates if these by-products are a significant source of extractable dietary phenols which could exhibit cellular antioxidants activity.Methods: Endogenous phenolic compounds obtained from canola oil deodistillates and canola meal using different extraction techniques were identified and examined for their in vitro antioxidant activities in "test tube" and cellular assays.Results: Sinapine was the predominant phenolic in the canola meal crude extract, while canolol was the only significant phenol in the accelerated solvent extract of canola meal.The deodistillate did not have canolol or sinapine present, but contained high molecular weight phenols of unknown identity.The "test tube" antioxidant assays indicated that canola meal crude extract and sinapic acid both exhibited stronger antioxidant potentials compared to the other extracts.A dose dependent cyto-protection effect was observed under oxidative challenge by H 2 O 2 , when cells were incubated with the canola meal accelerated solvent extract, deodistillate extract and sinapic acid.Conclusions: This study demonstrates that canola by-products can be the sources of health promoting phenols, for possible formulation into value added nutraceuticals.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".