MétaCan
Menu
Back to cohort
Record W2947203813 · doi:10.1126/sciadv.aav3058

Pre-conception maternal helminth infection transfers via nursing long-lasting cellular immunity against helminths to offspring

2019· article· en· W2947203813 on OpenAlexaff
Matthew Darby, Alisha Chetty, Dunja Mrjden, Marion Rolot, Katherine A. Smith, Claire Mackowiak, Delphine Sedda, Donald Nyangahu, Heather B. Jaspan, Kai‐Michael Toellner, Ari Waisman, Valérie Quesniaux, Bernhard Ryffel, Adam F. Cunningham, Benjamin G Dewals, Frank Brombacher, William Horsnell

Bibliographic record

VenueScience Advances · 2019
Typearticle
Languageen
FieldMedicine
TopicBreastfeeding Practices and Influences
Canadian institutionsInstitute of Infection and Immunity
FundersH2020 Marie Skłodowska-Curie ActionsBiotechnology and Biological Sciences Research CouncilMedical Research CouncilNational Science Foundation, United Arab EmiratesNational Research FoundationDeutsche ForschungsgemeinschaftCarnegie Corporation of New York
KeywordsOffspringHelminthsImmunityHelminth infectionsBiologyImmunologyPregnancyMedicineImmune systemGenetics

Abstract

fetched live from OpenAlex

2-competent CD4 T cells. Our data therefore reveal that maternal exposure to a globally prevalent source of infection before pregnancy provides long-term nursing-acquired immune benefits to offspring mediated by maternally derived pathogen-experienced lymphocytes.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.393
Threshold uncertainty score0.605

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.001
Science and technology studies0.0000.000
Scholarly communication0.0000.003
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.303
Teacher spread0.291 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations48
Published2019
Admission routes1
Has abstractyes

Explore more

Same venueScience AdvancesSame topicBreastfeeding Practices and InfluencesFrench-language works237,207