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Carotenoid Pigments of Red, Green and Brown Macroalgae Species as Potential Active Pharmaceutical Ingredients

2019· article· en· W2947390365 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

venuePublished in a venue whose home country is Canada.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueJournal of Pharmacy and Nutrition Sciences · 2019
Typearticle
Languageen
FieldAgricultural and Biological Sciences
TopicSeaweed-derived Bioactive Compounds
Canadian institutionsnot available
FundersInternational Islamic University Malaysia
KeywordsZeaxanthinViolaxanthinCarotenoidLuteinBiologyBotanyPigmentGreen algaeFood scienceChemistryAlgae

Abstract

fetched live from OpenAlex

Active Pharmaceutical Ingredient (API) is a substance used in a finished pharmaceutical product, intended to furnish pharmacological activity or contribute direct effect in the diagnosis, cure, mitigation, treatment or prevention of disease. It also provides a direct effect in restoring, correcting or modifying physiological functions in human beings. Macroalgae, also known as seaweed, are plant-like organisms that can be found in a marine habitat. Macroalgae has been given huge concern because of its high nutritional value and short-term growth, which is only 45 days per cycle. Therefore, three red macroalgae species of Eucheuma denticulatum, Gracilaria tikvahiae and Kappaphycus striatum), as well as green and brown macroalgae species of Caulerpa lentillifera and Padina pavonica were selected to determine their carotenoids content and composition by using UV-Vis spectrophotometer and HPLC analysis. The main carotenoids identified in red, green and brown macroalgae species were zeaxanthin, lutein, ?-carotene and violaxanthin. Marked differences were observed between red, green and brown macroalgae carotenoids content and composition. Zeaxanthin and ?-carotene were detected in all red, green and brown macroalgae ranged from 3.61 to 21.30 ?g/g DW and 2.44 to 10.70 ?g/g DW respectively. Violaxanthin was found only in green macroalgae (8.93 ?g/g DW) whereas lutein was found only in red macroalgae (9.57 to 38.60 ?g/g DW). In terms of total carotenoid content, green macroalgae contained the highest amount of carotenoid (100.89 ± 14.71 ?g/g DW). The significant outcome of the research will be new natural carotenoid pigment sources as potential active pharmaceutical ingredients which can be beneficial to halal health-promoting products industry.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.376
Threshold uncertainty score0.283

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.001
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.043
GPT teacher head0.306
Teacher spread0.263 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it