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Record W2947669686 · doi:10.3389/fneur.2019.00522

Efficacy of LVIS vs. Enterprise Stent for Endovascular Treatment of Medium-Sized Intracranial Aneurysms: A Hemodynamic Comparison Study

2019· article· en· W2947669686 on OpenAlexfundno aff
Wenqiang Li, Yang Wang, Yisen Zhang, Kun Wang, Ying Zhang, Zhongbin Tian, Xinjian Yang, Jian Liu

Bibliographic record

VenueFrontiers in Neurology · 2019
Typearticle
Languageen
FieldMedicine
TopicIntracranial Aneurysms: Treatment and Complications
Canadian institutionsnot available
FundersNanchang UniversityNational Natural Science Foundation of ChinaCapital Health
KeywordsEndovascular treatmentHemodynamicsMedicineRadiologyStentAneurysmCardiology

Abstract

fetched live from OpenAlex

Background: We conducted a computational fluid dynamics (CFD) study, compared the treatment of medium-sized intracranial aneurysms with LVIS and Enterprise stent assisted coil embolization (SACE) to determine the effects of hemodynamic changes caused by different stent and coil packing densities (PD) in endovascular treatment. Methods: We enrolled 87 consecutive patients, with 87 medium-sized intracranial aneurysms (≥7 mm, ≤12 mm), who underwent LVIS or Enterprise SACE. Aneurysms treated with LVIS SACE were allocated to the LVIS group, and the remainder to the Enterprise group. CFD were performed to assess hemodynamic alterations between before treatment, after stent deployment, and after SACE. Results: One aneurysm recanalized in the LVIS group (n=42) and five recanalized in the Enterprise group (n=45) (recanalization rate: 2.4% vs 11.1%, respectively; P=0.108). Higher complete obliteration rate (P=0.069) and PD (P=0.146) was found in the LVIS group. Velocity at the neck plane showed a greater reduction ratio than velocity and WSS of the aneurysm in both groups after stent deployment, while velocity and WSS of the aneurysm showed a greater reduction ratio after coil placement. Further, there was a greater reduction in velocity at the neck plane (59.52% vs 39.81%), aneurysmal velocity (88.46% vs 69.45%), and wall shear stress (WSS) (85.45% vs 69.49%) on the aneurysm in the LVIS group (P<0.001 for all). Specifically, the reduction ratio of velocity at the neck plane showed significant difference between the groups in the multivariate analysis (p=0.013). Conclusions: LVIS SACE showed a lower recanalization for endovascular treatment of medium-sized intracranial aneurysms, and the greater hemodynamic alterations might be the key factors.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.001
Threshold uncertainty score0.005

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.267
Teacher spread0.255 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations26
Published2019
Admission routes1
Has abstractyes

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