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Record W2948304504 · doi:10.1080/09581596.2019.1597966

Ebola vaccine innovation: a case study of pseudoscapes in global health

2019· article· en· W2948304504 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.
fundA Canadian funder is recorded on the work.

Bibliographic record

VenueCritical Public Health · 2019
Typearticle
Languageen
FieldMedicine
TopicViral Infections and Outbreaks Research
Canadian institutionsDalhousie University
FundersEuropean Investment BankNational Institutes of HealthCanadian Institutes of Health ResearchNorges ForskningsrådPublic Health Agency of Canada
KeywordsDeclarationGlobal healthPublic healthEbola vaccineSustainabilityWork (physics)Economic growthInvestment (military)BusinessPublic relationsPolitical scienceHealth careOutbreakMedicineEconomicsEbola virusVirologyEngineeringLaw

Abstract

fetched live from OpenAlex

Global vaccine development is driven by logics that can run counter to local understandings, needs, and contexts. In a global industrial complex, dependent on financial market logics that prioritize private enterprise, highly promising innovative health products developed in public laboratories may be shelved and revealed only when market opportunities attract investment interest. Such an opportunity arrived with the WHO declaration of a Public Health Emergency of International Concern in 2014. The West African Ebola outbreak mobilized a global platform to accelerate development of existing experimental vaccines. This article explores pseudo-authorship by industry of the rVSV-ZEBOV Ebola vaccine that disappeared its actual discovery by public scientists. It shows that vaccine development in a global health pseudoscape disguises the source and means of innovation, deflects resources to the private sector, and can hinder sustainability of health systems. Pseudo-collaborations give little credit to those who have done the risky work, and pseudo-capacity building seldom reaches the people on the ground needing general health systems. Pseudo-standards, however, may offer an opportunity to free evidence-based gold standards to better respond to public health emergencies.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.002
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.192
Threshold uncertainty score0.998

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0020.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.089
GPT teacher head0.482
Teacher spread0.393 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it