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Record W2948304504 · doi:10.1080/09581596.2019.1597966

Ebola vaccine innovation: a case study of pseudoscapes in global health

2019· article· en· W2948304504 on OpenAlexafffund
Janice Graham

Bibliographic record

VenueCritical Public Health · 2019
Typearticle
Languageen
FieldMedicine
TopicViral Infections and Outbreaks Research
Canadian institutionsDalhousie University
FundersEuropean Investment BankNational Institutes of HealthCanadian Institutes of Health ResearchNorges ForskningsrådPublic Health Agency of Canada
KeywordsDeclarationGlobal healthPublic healthEbola vaccineSustainabilityWork (physics)Economic growthInvestment (military)BusinessPublic relationsPolitical scienceHealth careOutbreakMedicineEconomicsEbola virusVirologyEngineeringLaw

Abstract

fetched live from OpenAlex

Global vaccine development is driven by logics that can run counter to local understandings, needs, and contexts. In a global industrial complex, dependent on financial market logics that prioritize private enterprise, highly promising innovative health products developed in public laboratories may be shelved and revealed only when market opportunities attract investment interest. Such an opportunity arrived with the WHO declaration of a Public Health Emergency of International Concern in 2014. The West African Ebola outbreak mobilized a global platform to accelerate development of existing experimental vaccines. This article explores pseudo-authorship by industry of the rVSV-ZEBOV Ebola vaccine that disappeared its actual discovery by public scientists. It shows that vaccine development in a global health pseudoscape disguises the source and means of innovation, deflects resources to the private sector, and can hinder sustainability of health systems. Pseudo-collaborations give little credit to those who have done the risky work, and pseudo-capacity building seldom reaches the people on the ground needing general health systems. Pseudo-standards, however, may offer an opportunity to free evidence-based gold standards to better respond to public health emergencies.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.010
metaresearch head score (Gemma)0.015
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesScience and technology studies
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Qualitative · Consensus signal: Qualitative
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.986
Threshold uncertainty score0.051

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0100.015
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.001
Bibliometrics0.0020.002
Science and technology studies0.0140.012
Scholarly communication0.0080.006
Open science0.0020.010
Research integrity0.0060.006
Insufficient payload (model declined to judge)0.0060.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.089
GPT teacher head0.482
Teacher spread0.393 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

Study designQualitative
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations25
Published2019
Admission routes2
Has abstractyes

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