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Record W2948605970 · doi:10.1093/ehjci/jez121.001

276Non contrast 3D steady-state free-precession magnetic resonance angiography: the more relevant magnetic resonance technique for the assessment prior to Ross procedure?

2019· article· en· W2948605970 on OpenAlexaff
Fabien Labombarda, Marien Lenoir, Sumaira Aslam, F Marcotte, I. El-Hamamsy, François Pierre Mongeon

Bibliographic record

VenueEuropean Heart Journal - Cardiovascular Imaging · 2019
Typearticle
Languageen
FieldMedicine
TopicAdvanced MRI Techniques and Applications
Canadian institutionsMontreal Heart Institute
Fundersnot available
KeywordsSteady-state free precession imagingCardiac skeletonMedicineMagnetic resonance angiographyAortaVentricular outflow tractMagnetic resonance imagingRadiologyNuclear medicineCardiologyAortic root

Abstract

fetched live from OpenAlex

Background : Accurate evaluation of the native aortic annulus or left ventricular outflow tract (LVOT) dimensions is critical for planning aortic root interventions. We use cardiovascular magnetic resonance (CMR) for assessment of the aortic root dimensions prior to the Ross procedure. Non-contrast 3D steady-state free-precession magnetic resonance angiography (3D-SSFP MRA) with electrocardiographic and respiratory gating is a safe and accurate technique to evaluate the entire aorta. Purpose: 1) To determine the agreement between two CMR measurements (3D-SSFP MRA and cine SSFP) and direct in-vivo measurement of the aortic annulus, 2) To evaluate the ability of preoperative CMR to predict the need for aortic annuloplasty. Methods: We retrospectively included patients who had a comprehensive CMR exam as preoperative assessment for a Ross procedure and intraoperative aortic annulus diameter measurement using Hegar dilators. CMR exams (1.5T scanner) were performed using a dedicated protocol including orthogonal long-axis LVOT cine-CMR images, double-oblique short-axis LVOT cine images planned from these views and a 3D-SSFP MRA covering the LVOT and thoracic aorta. Considering the elliptical shape of the aortic annulus, minimal and maximal aortic annulus (LVOT) diameters were measured and averaged in long-axis cine-CMR, in short-axis cine-CMR and from multiplanar reconstructed 3D-SSFP MRA images (Figure, left panel). Agreement between CMR and in-vivo aortic annulus measurements was assessed by Bland-Altman analysis. Results: We identified 44 patients (mean age 40.5 [23-62] years, 21 females, 29 aortic stenoses, 5 aortic regurgitations, 10 mixed aortic diseases, 25 aortic aneurysms) with complete records. All patients had a congenitally abnormal aortic valve (19 unicuspid, 24 bicuspid, 1 quadricuspid aortic valves). Close agreement was observed between minimal 3D-SSFP MRA LVOT diameter and in-vivo aortic annulus diameter (bias -0.7 95%CI -1.2 to -0.2 mm; limits of agreement (LoA) -4.20 to 2.75 mm, Figure middle panel) and between mean 3D-SSFP MRA LVOT diameter and in-vivo aortic annulus diameter (2.1, 1.6 to 2.6 mm; LoA -1.07 to 5.31 mm). Minimal 3D-SSFP MRA LVOT diameter best predicted the need for aortic annuloplasty (area under the curve 0.88, 95% CI 0.87-0.91, Figure right panel). Conclusion: Mean and minimal 3D-SSFP MRA LVOT diameters best agree with the aortic annulus diameter measured in-vivo. Minimal 3D-SSFP LVOT diameter may be the more relevant measurement for planning aortic annuloplasty as part of a Ross procedure. CMR aortic annulus or LVOT measurements should be obtained from multiplanar reconstruction of gated 3D datasets. Abstract 276 Figure. Non contrast 3D MRI and Ross procedure

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.908
Threshold uncertainty score0.915

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.001
Bibliometrics0.0000.001
Science and technology studies0.0010.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.013
GPT teacher head0.304
Teacher spread0.291 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designOther design
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2019
Admission routes1
Has abstractyes

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