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Record W2948672718 · doi:10.1242/jeb.206557

Influence of stretch magnitude on the stretch-shortening cycle in skinned fibres

2019· article· en· W2948672718 on OpenAlexafffund
Atsuki Fukutani, Walter Herzog

Bibliographic record

VenueJournal of Experimental Biology · 2019
Typearticle
Languageen
FieldEngineering
TopicMuscle activation and electromyography studies
Canadian institutionsUniversity of Calgary
FundersCanada Research ChairsJapan Society for the Promotion of ScienceKillam TrustsCanadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of CanadaNakatomi Foundation
KeywordsSarcomereStretch shortening cycleMaterials scienceContraction (grammar)Work (physics)ChemistryAnatomyPhysicsBiologyInternal medicineMyocyteMedicine

Abstract

fetched live from OpenAlex

The mechanical work attained during shortening is increased by prior stretching. Recently, we suggested that the residual force enhancement (RFE) may contribute to this enhanced work. RFE can be changed reliably by changing the stretch magnitude. Therefore, the purpose of this study was to examine the effect of stretch magnitude, and by association of RFE, on the mechanics of the stretch-shortening cycle in skinned skeletal muscle fibres. Three tests were performed using skinned rabbit soleus fibres (N=18). The first test was a pure shortening contraction in which fibers were activated and then shortened from an average sarcomere length of 3.3 to 3.0 µm. The second test was a SSC in which fibers were activated and stretched from 3.0 µm to 3.3 µm, and then shortened to 3.0 µm. The third test was a SSC in which fibers were activated and stretched from 2.4 to 3.3, and then shortened to 3.0 µm. The mechanical work during shortening and the force maintained 15 s after the end of shortening were determined. The relative increase in mechanical work with respect to the pure shortening condition, was greater for the large than the small stretch condition (p<0.001). Similarly, the relative increase in force 15 s after the end of shortening was greater for the large than the small stretch condition (p=0.043). We conclude that increasing the magnitude of stretch results in an increase in mechanical work and increased force at steady-state following the stretch, likely because of the greater RFE.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.006

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.008
GPT teacher head0.247
Teacher spread0.239 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations16
Published2019
Admission routes2
Has abstractyes

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