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Record W2952056892

A Policy Analysis to Inform Options for Medical Device Regulation and Post-Market Surveillance in the Canadian Context

2018· article· en· W2952056892 on OpenAlexaboutno aff
Agnetha de

Bibliographic record

VenueSummit (Simon Fraser University) · 2018
Typearticle
Languageen
FieldMedicine
TopicBiotechnology and Related Fields
Canadian institutionsnot available
Fundersnot available
KeywordsContext (archaeology)BusinessPublic relationsPolitical scienceHistory
DOInot available

Abstract

fetched live from OpenAlex

With ageing populations and rising rates of chronic diseases, medical devices are increasingly vital components of health care. From tongue depressors and stethoscopes to pacemakers and medical robotics, medical devices are numerous, diverse and constantly evolving, integrating medicine, biomechanics, materials, software, and electronics in their development and application (Chen et al., 2018). However, while innovation is generally beneficial for patients, the complexity and diversity of medical devices poses a challenge for regulatory systems across the globe, which are often slow to adapt to the increasing complexity of medical devices, unpredictable risks, and emerging threats to public health (Curfman and Redberg, 2011; Mishra, 2017; Chen et al., 2018). Consequently, with medical device failures and malfunctions appearing in media and academic journals there is a global push for stricter regulatory reform and harmonization of regulatory frameworks internationally (Curfman and Redberg, 2011; Altenstetter, 2012; Maak & Wylie, 2016; Chen et al., 2018). This capstone will review and compare the regulatory frameworks for three jurisdictions (Canada, the United States and the European Union) with an aim of identifying post-market strategies which could be applicable to the Canadian context. Additionally the current and proposed changes to the Canadian medical device regulations will be discussed and analysed across multiple dimensions (burdens on various actors, innovation vs regulatory oversight and health risk protection) and, the 3-I framework will be used to deepen the understanding behind the shift in regulatory approach that Health Canada is working to implement. Lastly, based on the regulatory approaches compared and analysed it will provide an informed opinion on the approach that Health Canada is taking.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.942
Threshold uncertainty score0.959

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.002
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0010.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.009
GPT teacher head0.243
Teacher spread0.234 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations1
Published2018
Admission routes1
Has abstractyes

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