UJI AKTIVITAS ANTIPIRETIK EKSTRAK DAUN SISIK NAGA(Pyrrosia piloselloides (L.) M.G. Price) TERHADAP TIKUS PUTIH (Rattus norvegicus) JANTAN GALUR WISTAR YANG DIINDUKSI PEPTON 5%
Bibliographic record
Abstract
INTISARI Demam adalah keadaan ketika suhu tubuh meningkat melebihi suhu tubuh normal. Demam terjadi karena pelepasan pirogen dari dalam leukosit yang sebelumnya telah terangsang oleh pirogen eksogen yang dapat berasal dari mikroorganisme atau merupakan suatu hasil reaksi imunologik yang tidak berdasarkan suatu infeksi. Sementara itu, banyak negara telah mengembangkan pengobatan menggunakan herbal. Salah satu usaha yang dilakukan adalah dengan penggunaan obat tradisional. Penelitian ini bertujuan untuk membuktikan bahwa daun Sisik Naga (Pyrrosia piloselloides (L.) M.G Price) dengan konsentrasi 0,062%, 0,125% dan 0,25% memiliki aktivitas antipiretik dengan menggunakan penginduksi demam Pepton 5%. Penelitian ini merupakan penelitian eksperimental dengan Rancang Acak Lengkap (RAL). Pengukuran suhu rektal tikus menggunakan termometer infra red. Hewan uji dibagi menjadi 5 kelompok yaitu kelompok kontrol negatif (suspensi Na-CMC 1%), kelompok kontrol positif (suspensi parasetamol) dan kelompok uji yaitu pemberian ekstrak daun sisik naga 0,062%, 0,125% dan 0,25%. Data yang diperoleh dianalisis dengan menggunakan uji anova dan uji LSD (Least Significant Different). Hasil dari penelitian ini bahwa ekstrak daun sisik naga (Pyrrosia piloselloides (L.) M.G Price) konsentrasi 0,25% mempunyai aktivitas antipiretik pada tikus putih (Rattus norvegicus) jantan galur wistar. Kata kunci: Antipiretik, Daun Sisik Naga (Pyrrosia piloselloides (L.) M.G Price), Pepton 5% ABSTRACT A fever is a condition when the body temperature rises beyond the normal body temperature. Fever occurs due to the release of pyrogytes from within leukocytes that have previously been stimulated by exogenous pyrogens that may originate from microorganisms or are a result of immunologic reactions that are not based on an infection. Meanwhile, many countries have developed treatments using herbs. One of the efforts done is with the use of traditional medicine. This study aims to prove that the leaves of the Dragon Scales (Pyrrosia piloselloides (L.) M.G Price) with concentrations of 0.062%, 0.125% and 0.25% have antipyretic activity using Pepton fever induction 5%. This research is an experimental research with Completely Random Design (RAL). Rectal temperature measurements of mice using infra red thermometer. Test animals were divided into 5 groups: negative control group (1% Na-CMC suspension), positive control group (paracetamol suspension) and the test group were 0.062%, 0.125% and 0.25%. The data obtained were analyzed using anova test and LSD (Least Significant Different) test. The results of this study showed that the extract of leaf scales (Pyrrosia piloselloides (L.) M.G Price) concentrations of 0.25% had antipyretic activity in white rats (Rattus norvegicus) male wistar strain. Keywords: Antipyretics, Leaf Scales Dragon (Pyrrosia piloselloides (L.) M.G Price), Pepton 5%
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.003 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".