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Record W2955014846 · doi:10.1002/pd.5517

Uterine artery and umbilical vein blood flow are unaffected by moderate habitual physical activity during pregnancy

2019· article· en· W2955014846 on OpenAlexafffund
Dafna Sussman, Brahmdeep S. Saini, Jane E. Schneiderman, Rachel F. Spitzer, Mike Seed, Stephen J. Lye, Greg D. Wells

Bibliographic record

VenuePrenatal Diagnosis · 2019
Typearticle
Languageen
FieldMedicine
TopicPregnancy and preeclampsia studies
Canadian institutionsLunenfeld-Tanenbaum Research InstituteMount Sinai HospitalUniversity of TorontoSickKids FoundationHospital for Sick ChildrenYork University
FundersCanadian Institutes of Health Research
KeywordsHemodynamicsMedicineBlood flowCardiologyPregnancyPhysical fitnessInternal medicinePhysical therapyBiology

Abstract

fetched live from OpenAlex

Abstract Objective This study aims to noninvasively quantify blood flow in the uterine arteries (UTAs) and umbilical vein (UV) using phase‐contrast magnetic resonance imaging (PC‐MRI) and test whether these correlate with maternal fitness parameters. Method Resting UTA and UV flows were measured in 23 healthy 30 ± 3‐year‐old women who engaged in moderate‐intensity physical activity during pregnancy. Participant fitness was characterized in the second and third trimesters using the submaximal oxygen uptake (VO 2 ) test measuring heart rate (HR), VO 2 , ventilation (ventilatory equivalent [VE]/VO 2 ), and the Borg rating of perceived exertion (respiratory quotient [RQ]). Linear regression models were used to determine the associations between blood flow and maternal fitness measures. Results Blood flows in the UTA (957 ± 241 mL/min) and UV (132 ± 38 mL/min/kg) were successfully measured in 20 (87%) participants. Neither was associated with any physical fitness parameters (HR, VO 2 , VE/VO 2 , and RQ) nor with any second‐to‐third trimester change in these parameters. Conclusion PC‐MRI can be used to noninvasively measure blood flow in the UTA and UV. Neither resting UTA nor UV flow is associated with maternal fitness parameters. This is the first MRI–based study to provide novel hemodynamic data suggesting decoupling between maternal moderate fitness level and the maternal‐placental‐fetal hemodynamic system in healthy, normal body mass index (BMI) pregnancies.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.245
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.247
Teacher spread0.237 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations11
Published2019
Admission routes2
Has abstractyes

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