Deep Radiomic Analysis Based on Modeling Information Flow in Convolutional Neural Networks
Bibliographic record
Abstract
This paper proposes a novel image feature set based on a principled information theoretic analysis of the convolutional neural network (CNN). The output of convolutional filters is modeled as a random variable conditioned on the object class and network filter bank. The conditional entropy (CENT) of filter outputs is shown in theory and experiments to be a highly compact and class-informative feature that can be computed from the CNN feature maps and used to obtain higher classification accuracy than the original CNN itself. Experiments involve three binary classification tasks using the 3D brain MRI data: Alzheimer's disease (AD) versus healthy controls (HC), young versus old age, and male versus female, where the area under the curve (AUC) values for the CENT feature classification (93.9%, 96.7%, and 71.9%) are significantly higher than the softmax output of the original CNN classifier trained for the task (81.6%, 79.4%, and 63.1%). A statistical analysis based on the Wilcoxon test identifies CENT features with significant links to brain labels, which could potentially serve as diagnostic biomarkers.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".