Greater Stimulation of Postexercise Muscle Protein Synthesis after Consumption of Whole Eggs versus Egg Whites in Healthy Young Men
Bibliographic record
Abstract
The majority of protein consumed in the diet is obtained from whole food sources that contain a mixture of macro‐ and micronutrients. Whereas the majority of research investigated the effect of isolated protein sources on protein metabolism, our aim was to assess the muscle anabolic potential of consuming a complete protein within its naturally occurring, nutrient dense food matrix during recovery from resistance exercise in young men. In crossover trials, 10 healthy resistance‐trained men (21±1 y; 88±3 kg; bodyfat: 16±1%) received primed continuous L‐[ ring ‐ 2 H 5 ]phenylalanine and L‐[1‐ 13 C]leucine infusions. Repeated blood and muscle biopsies were collected before and after a single bout of resistance exercise (4 sets of 10 repetitions at 80% of 10‐RM for both leg press and leg extensions). Immediately after resistance exercise, participants ingested intrinsically L‐[5,5,5‐ 2 H 3 ]leucine labeled whole eggs (18 g protein, 17 g fat) or egg whites (18 g protein, 0 g fat) cooked in scrambled form. Exogenous leucine appearance rates increased ( P <0.001) after protein ingestion with peak values of 513±57 nmol leucine·kg −1 ·min −1 occurring at 75 min after egg white ingestion compared with 496±38 nmol leucine·kg −1 ·min −1 at 120 min after whole egg ingestion. The total amount of protein derived leucine that became available in circulation over the 300 min postprandial period was similar ( P= 0.53) between whole egg (75±2.3%) and egg white ingestion (77±1.7%). Whole egg ingestion supported greater post‐exercise myofibrillar protein synthesis rates when compared to egg white ingestion (0.034%/h and 0.024%/h respectively; P =0.02). We conclude that whole egg ingestion stimulates the muscle protein synthetic response more effectively than the consumption of isonitrogenous amounts of egg whites during recovery from resistance exercise in healthy young men. This effect is not attributed to divergent postprandial protein‐derived amino acid availability, suggesting that some intrinsic factor within whole eggs and/or the divergent macronutrient profile may have modified the anabolic potential of this complete protein. Support or Funding Information Vision 20/20 Grant, Division of Nutritional Sciences, University of Illinois, Urbana‐Champaign
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".