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Record W2967318921 · doi:10.1645/18-170

Effects of a Cyanobacterial Toxin on Trematode Cercariae

2019· article· en· W2967318921 on OpenAlexaff
Marin Milotic, Dino Milotic, Janet Koprivnikar

Bibliographic record

VenueJournal of Parasitology · 2019
Typearticle
Languageen
FieldEnvironmental Science
TopicParasite Biology and Host Interactions
Canadian institutionsToronto Metropolitan University
Fundersnot available
KeywordsBiologyParasite hostingZoologyHost (biology)EutrophicationIntermediate hostEcologyLongevityTrematodaHelminths

Abstract

fetched live from OpenAlex

Eutrophication of aquatic habitats has become a global problem, with implications for host–parasite dynamics. Blooms of certain cyanobacteria are associated with cyanotoxins, particularly microcystins such as microcystin-LR (MC-LR). These potent toxins have been shown to adversely affect freshwater fauna and can increase host susceptibility to parasite infection. However, to understand how cyanotoxins influence infection outcomes in nature, it is necessary to investigate whether free-living parasite infectious stages, such as that of trematode cercariae, are also affected given their demonstrated sensitivity to various contaminants. Here we examined the effects of environmentally relevant levels of MC-LR representing relatively high (82 µg/L) and low (11 µg/L) concentrations on the activity and survival of four different types of cercariae (Echinostoma sp., Cephalogonimus sp., Alaria sp., and an unidentified strigeid type) over 24 hr. Exposure to MC-LR did not affect the activity of any cercarial type, nor was survival reduced. In fact, the strigeid-type cercariae had significantly increased longevity if exposed to either MC-LR solution, with the greatest longevity in the highest concentration. Our results indicate that MC-LR may have opposing effects on aquatic parasites and their hosts, potentially increasing host susceptibility but having a neutral or positive effect on motile infectious stages such as cercariae. Cyanobacterial blooms could thus enhance trematode transmission; however, the effects of other cyanotoxins must be studied, as well as a broader range of host and parasite species.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.371
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.313
Teacher spread0.307 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations8
Published2019
Admission routes1
Has abstractyes

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